Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721179 | 0.98 | L3MBTL1 (0.50) | L3MBTL1HRH3ACACBACHECDC7 | |
| SCHEMBL14721980 | 0.88 | HRH3 (0.43) | L3MBTL1HRH3GRIA2SRD5A2KMT2A | |
| SCHEMBL14720854 | 0.85 | HRH3 (0.40) | L3MBTL1HRH3GRIA2SRD5A2 | |
| SCHEMBL14722442 | 0.82 | GRM2 (0.47) | L3MBTL1HRH3SRD5A2LTA4HKMT2A | |
| SCHEMBL14720649 | 0.82 | FKBP1A (0.35) | L3MBTL1HRH3SRD5A2KMT2AALDH1A1 | |
| SCHEMBL14720524 | 0.80 | PDE4A (0.35) | L3MBTL1SRD5A2CYP2C9MAPK1ALDH1A1 | |
| SCHEMBL14720525 | 0.80 | PDE4A (0.35) | L3MBTL1SRD5A2CYP2C9MAPK1ALDH1A1 | |
| SCHEMBL14720875 | 0.80 | FKBP1A (0.38) | HRH3SRD5A2KCNH2 | |
| SCHEMBL14720876 | 0.80 | FKBP1A (0.38) | HRH3SRD5A2KCNH2 | |
| SCHEMBL14720575 | 0.80 | L3MBTL3 (0.51) | L3MBTL1HRH3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |