Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 12/20 | 0.55 |
| ▸ | PRKCA | P17252 | 12/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 9/20 | 0.53 |
| ▸ | GSK3B | P49841 | 5/20 | 0.49 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | STK10 | O94804 | 1/20 | 0.46 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844233 | 0.85 | PRKCB (0.74) | PRKCBPRKCAPRKCEGSK3BPRKD1 | |
| SCHEMBL7840192 | 0.84 | PRKCA (0.76) | PRKCBPRKCAPRKCEGSK3BPRKD1 | |
| SCHEMBL14722003 | 0.83 | GSK3B (0.48) | PRKCBPRKCAPRKCEGSK3BSTK10 | |
| SCHEMBL7839690 | 0.80 | JAK2 (0.77) | PRKCBPRKCAPRKCEGSK3BQPCT | |
| SCHEMBL7840914 | 0.71 | PRKCB (0.87) | PRKCBPRKCAPRKCEGSK3BJAK2 | |
| SCHEMBL14041503 | 0.71 | GSK3B (0.62) | GSK3BPRKD1TDP1QPCT | |
| SCHEMBL7842250 | 0.71 | PRKCA (1.00) | PRKCBPRKCAPRKCEGSK3BPRKD1 | |
| SCHEMBL14721743 | 0.71 | GSK3B (0.53) | PRKCBPRKCAPRKCEGSK3B | |
| SCHEMBL5819295 | 0.70 | PRKCB (0.74) | PRKCBPRKCAGSK3BJAK2JAK1 | |
| SCHEMBL9085883 | 0.70 | PRKD1 (0.79) | PRKCBPRKCAPRKCEGSK3BPRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029043-A1 | SELECTIVE KINASE INHIBITORS | REACTION BIOLOGY CORP. (US) | 2013-02-28 | — | — | WO | disclosed |