Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 13/20 | 0.76 |
| ▸ | PRKCB | P05771 | 12/20 | 0.76 |
| ▸ | PRKCE | Q02156 | 8/20 | 0.76 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | GSK3B | P49841 | 3/20 | 0.60 |
| ▸ | PRKACA | P17612 | 2/20 | 0.57 |
| ▸ | PRKACG | P22612 | 2/20 | 0.57 |
| ▸ | PRKACB | P22694 | 2/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | PRKCH | P24723 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844233 | 0.89 | PRKCB (0.74) | PRKCAPRKCBPRKCEPRKD1TDP1 | |
| SCHEMBL7830800 | 0.87 | PRKCA (1.00) | PRKCAPRKCBPRKCEPRKD1TDP1 | |
| SCHEMBL7843214 | 0.84 | PRKCA (1.00) | PRKCAPRKCBPRKCEPRKD1TDP1 | |
| SCHEMBL14722002 | 0.84 | PRKCB (0.55) | PRKCAPRKCBPRKCEPRKD1TDP1 | |
| SCHEMBL8120702 | 0.84 | PRKCA (0.80) | PRKCAPRKCBPRKCEPRKD1TDP1 | |
| SCHEMBL7839690 | 0.83 | JAK2 (0.77) | PRKCAPRKCBPRKCEGSK3BJAK2 | |
| SCHEMBL7842630 | 0.81 | PRKCA (0.89) | PRKCAPRKCBPRKCEPRKD1TDP1 | |
| SCHEMBL1680253 | 0.81 | PRKD1 (1.00) | PRKCAPRKCBPRKCEPRKD1TDP1 | |
| SCHEMBL29353099 | 0.81 | PRKD1 (1.00) | PRKCAPRKCBPRKCEPRKD1TDP1 | |
| SCHEMBL29525501 | 0.81 | PRKD1 (1.00) | PRKCAPRKCBPRKCEPRKD1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | claimed |
| WO-2013029043-A1 | SELECTIVE KINASE INHIBITORS | REACTION BIOLOGY CORP. (US) | 2013-02-28 | — | — | WO | disclosed |
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | disclosed |