Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.48 |
| ▸ | STK10 | O94804 | 7/20 | 0.47 |
| ▸ | SLK | Q9H2G2 | 7/20 | 0.47 |
| ▸ | PRKCB | P05771 | 7/20 | 0.45 |
| ▸ | PRKCA | P17252 | 6/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722002 | 0.83 | PRKCB (0.55) | GSK3BSTK10SLKPRKCBPRKCA | |
| SCHEMBL7844233 | 0.77 | PRKCB (0.74) | GSK3BPRKCBPRKCAPRKCE | |
| SCHEMBL7840192 | 0.76 | PRKCA (0.76) | GSK3BPRKCBPRKCAPRKCE | |
| SCHEMBL7839690 | 0.72 | JAK2 (0.77) | GSK3BPRKCBPRKCAPRKCE | |
| SCHEMBL5819295 | 0.71 | PRKCB (0.74) | GSK3BSTK10SLKPRKCBPRKCA | |
| SCHEMBL14721745 | 0.71 | PRKCB (0.52) | GSK3BPRKCBPRKCAPRKCE | |
| SCHEMBL7781089 | 0.67 | GSK3B (1.00) | GSK3BSTK10SLK | |
| SCHEMBL7502631 | 0.66 | GSK3B (0.70) | GSK3BPRKCA | |
| SCHEMBL8161651 | 0.66 | GSK3B (0.80) | GSK3BPRKCA | |
| SCHEMBL9085883 | 0.65 | PRKD1 (0.79) | GSK3BPRKCBPRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029043-A1 | SELECTIVE KINASE INHIBITORS | REACTION BIOLOGY CORP. (US) | 2013-02-28 | — | — | WO | disclosed |