Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722106 | 0.88 | TUBB4A (0.34) | — | |
| SCHEMBL14722871 | 0.83 | ACLY (0.34) | MEN1KMT2A | |
| SCHEMBL14722345 | 0.81 | KDM4E (0.35) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14722314 | 0.80 | CYP1A2 (0.34) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14721954 | 0.79 | KDM4E (0.33) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14722909 | 0.79 | TUBB4A (0.33) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14721421 | 0.76 | PDE4A (0.36) | MAPT | |
| SCHEMBL14721807 | 0.74 | KDM4E (0.39) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14721728 | 0.73 | DRD2 (0.31) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14722126 | 0.70 | NPSR1 (0.35) | KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |