Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 9/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722106 | 0.86 | TUBB4A (0.34) | — | |
| SCHEMBL14722154 | 0.83 | KDM4E (0.31) | MEN1KMT2A | |
| SCHEMBL14722316 | 0.80 | MEN1 (0.35) | ACLYRXFP1MEN1POLBKMT2A | |
| SCHEMBL14721210 | 0.73 | KDM4E (0.37) | ACLYRXFP1MEN1POLBKMT2A | |
| SCHEMBL14721728 | 0.73 | DRD2 (0.31) | MEN1KMT2A | |
| SCHEMBL14725525 | 0.73 | BTK (0.37) | ALDH1A1BTK | |
| SCHEMBL14723431 | 0.70 | KDM4E (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL14722069 | 0.69 | TUBB1 (0.39) | MEN1KMT2A | |
| SCHEMBL14725387 | 0.68 | EPHX2 (0.38) | KMT2A | |
| SCHEMBL14722314 | 0.68 | CYP1A2 (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |