Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | OGT | O15294 | 1/20 | 0.60 |
| ▸ | UTRN | P46939 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14384814 | 0.87 | HSD17B1 (0.69) | SMN1; SMN2L3MBTL1UTRNKMT2AMEN1 | |
| SCHEMBL1176635 | 0.85 | MEN1 (0.69) | SMN1; SMN2HTTL3MBTL1UTRNKMT2A | |
| Anthracene SCHEMBL29076817 | 0.84 | MEN1 (0.67) | SMN1; SMN2HTTL3MBTL1UTRNKMT2A | |
| SCHEMBL171741 | 0.81 | L3MBTL1 (0.83) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL3818831 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8549110 | 0.80 | RAB9A (0.62) | SMN1; SMN2HTTL3MBTL1UTRNKMT2A | |
| Acetanilide SCHEMBL8761741 | 0.79 | NAPRT (0.86) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL9762638 | 0.79 | SMN1; SMN2 (0.86) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8577619 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL26613449 | 0.79 | MAPK10 (0.57) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | claimed |