Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14731024 | 0.97 | THRB (0.44) | THRBTGFBR1HTR2AHTR2CHTR2B | |
| SCHEMBL14731127 | 0.96 | THRB (0.44) | THRBTGFBR1HTR2AHTR2CHTR2B | |
| SCHEMBL14731126 | 0.91 | LMNA (0.41) | THRBTGFBR1HTR2AHTR2CHTR2B | |
| SCHEMBL14731001 | 0.90 | TGFBR1 (0.46) | THRBTGFBR1HTR2AHTR2CHTR2B | |
| SCHEMBL14731017 | 0.90 | HTR2A (0.45) | THRBTGFBR1HTR2AHTR2CHTR2B | |
| SCHEMBL14722704 | 0.88 | LMNA (0.44) | THRBTGFBR1HTR2AHTR2CHTR2B | |
| SCHEMBL14731096 | 0.88 | HRH3 (0.55) | THRBTGFBR1HTR2AHTR2CHTR2B | |
| SCHEMBL14731022 | 0.87 | MAPT (0.42) | HPGDMAPTCCR1CCR8ALDH1A1 | |
| SCHEMBL14731033 | 0.87 | TGFBR1 (0.46) | THRBTGFBR1HTR2AHTR2CHTR2B | |
| SCHEMBL14731019 | 0.87 | CCR1 (0.37) | THRBTGFBR1MAPTHRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026900-A1 | PYRIDINE DERIVATIVES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |