Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.44 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14731127 | 0.99 | THRB (0.44) | THRBTGFBR1HRH2HRH3HTR2A | |
| SCHEMBL14731015 | 0.97 | THRB (0.44) | THRBTGFBR1HRH2HRH3HTR2A | |
| SCHEMBL14722704 | 0.91 | LMNA (0.44) | THRBTGFBR1HRH2HRH3HTR2A | |
| SCHEMBL14731023 | 0.90 | HTR2A (0.45) | TGFBR1HRH2HRH3HTR2AHTR2C | |
| SCHEMBL14731033 | 0.90 | TGFBR1 (0.46) | THRBTGFBR1HRH2HRH3HTR2A | |
| SCHEMBL14731125 | 0.90 | LMNA (0.43) | THRBTGFBR1HRH2HRH3HTR2A | |
| SCHEMBL14731137 | 0.89 | HTR2A (0.44) | TGFBR1HRH2HRH3HTR2AHTR2C | |
| SCHEMBL14731036 | 0.89 | TGFBR1 (0.46) | THRBTGFBR1HRH2HRH3HTR2A | |
| SCHEMBL14731126 | 0.88 | LMNA (0.41) | THRBTGFBR1HRH2HRH3HTR2A | |
| SCHEMBL14731059 | 0.88 | HRH3 (0.58) | THRBTGFBR1HRH2HRH3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026900-A1 | PYRIDINE DERIVATIVES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |