Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 5/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722870 | 0.85 | OGA (0.40) | OGASMPD1RAB9ASRD5A2 | |
| SCHEMBL14720755 | 0.84 | HRH3 (0.40) | HRH3CYP2D6KMT2AMEN1RAB9A | |
| SCHEMBL14720972 | 0.73 | HRH3 (0.42) | HRH3CYP2D6SRD5A2 | |
| SCHEMBL14722348 | 0.72 | HRH3 (0.38) | HRH3CYP2D6KMT2AMEN1RAB9A | |
| SCHEMBL14722974 | 0.72 | HRH3 (0.39) | HRH3CYP2D6 | |
| SCHEMBL14720430 | 0.71 | SRD5A2 (0.43) | HRH3KMT2AKDM2BSRD5A2 | |
| SCHEMBL14721047 | 0.71 | GPR119 (0.42) | OGASMPD1 | |
| SCHEMBL14721400 | 0.71 | SRD5A2 (0.48) | OGAHRH3KMT2AKDM2BSRD5A2 | |
| SCHEMBL14731083 | 0.70 | SRD5A2 (0.46) | HRH3KMT2ARAB9ASRD5A2 | |
| SCHEMBL14720688 | 0.70 | GPR119 (0.41) | OGASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |