Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | YAP1 | P46937 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721047 | 0.91 | GPR119 (0.42) | GPR119OGASMPD1YAP1HDAC2 | |
| SCHEMBL14722713 | 0.89 | GPR119 (0.40) | GPR119OGASMPD1HDAC2GRM5 | |
| SCHEMBL14720595 | 0.79 | GPR119 (0.48) | GPR119OGAHDAC2GRM5 | |
| SCHEMBL1602307 | 0.76 | OGA (0.46) | GPR119PKMOGAHDAC2GRM5 | |
| SCHEMBL14722870 | 0.76 | OGA (0.40) | OGASMPD1HDAC2 | |
| SCHEMBL7368481 | 0.75 | FAAH (0.45) | GPR119PKM | |
| SCHEMBL15441571 | 0.75 | YAP1 (0.52) | GPR119YAP1HDAC2 | |
| SCHEMBL7447685 | 0.74 | SCN9A (0.47) | GPR119PKM | |
| SCHEMBL14720589 | 0.74 | GRM5 (0.43) | GPR119OGAHDAC2GRM5 | |
| SCHEMBL7450118 | 0.74 | GPR119 (0.51) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |