SCHEMBL14722870 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	OGA	O60502	12/20	0.40

▸	SMPD1	P17405	2/20	0.40

▸	SRD5A1	P18405	1/20	0.37

▸	RAB9A	P51151	1/20	0.36

▸	SMN1; SMN2	Q16637	1/20	0.36

▸	SRD5A2	P31213	2/20	0.35

▸	HDAC2	Q92769	1/20	0.35

▸	CCNT1	O60563	1/20	0.34

▸	CDK9	P50750	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14722713	0.88	GPR119 (0.40)	OGASMPD1HDAC2
SCHEMBL14722832	0.85	OGA (0.38)	OGASMPD1RAB9ASRD5A2
SCHEMBL14721047	0.79	GPR119 (0.42)	OGASMPD1SRD5A1HDAC2
SCHEMBL14720688	0.76	GPR119 (0.41)	OGASMPD1HDAC2
SCHEMBL28098574	0.71	GSK3B (0.51)	SRD5A1RAB9AHDAC2
SCHEMBL14720576	0.69	SRD5A1 (0.52)	OGASRD5A1SRD5A2HDAC2
SCHEMBL14722165	0.68	SRD5A1 (0.51)	OGASRD5A1SRD5A2HDAC2
SCHEMBL14720706	0.68	SRD5A1 (0.51)	OGASRD5A1SRD5A2HDAC2
SCHEMBL14720755	0.67	HRH3 (0.40)	RAB9A
SCHEMBL22683282	0.67	SRD5A1 (0.50)	OGASRD5A1SRD5A2HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013027001-A1	COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS	TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP)	2013-02-28	—	—	WO	disclosed