Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.33 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721035 | 0.74 | MCHR1 (0.36) | MCHR1 | |
| SCHEMBL14720311 | 0.74 | MCHR1 (0.38) | MCHR1 | |
| SCHEMBL14720920 | 0.71 | HRH3 (0.47) | MCHR1 | |
| SCHEMBL14720608 | 0.71 | HRH3 (0.43) | MCHR1 | |
| SCHEMBL17684271 | 0.71 | HSD11B1 (0.40) | — | |
| SCHEMBL14720913 | 0.69 | GPR183 (0.38) | MCHR1 | |
| SCHEMBL3393951 | 0.69 | KDM1A (0.34) | VHLELOCELOB | |
| SCHEMBL22804939 | 0.68 | DRD2 (0.32) | VHLELOCELOB | |
| SCHEMBL14722284 | 0.68 | HRH3 (0.44) | MCHR1 | |
| SCHEMBL14722836 | 0.68 | HRH3 (0.41) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |