Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723332 | 1.00 | MEN1 (0.41) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL26734448 | 0.93 | LTA4H (0.41) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL5514418 | 0.91 | HRH3 (0.44) | GAAPRMT1F2ST14HRH3 | |
| SCHEMBL9570661 | 0.91 | HRH3 (0.44) | GAAPRMT1F2ST14HRH3 | |
| SCHEMBL11234303 | 0.87 | ALDH1A1 (0.50) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL17215124 | 0.83 | GAA (0.43) | KMT2AALDH1A1GAAHRH3KCNH2 | |
| SCHEMBL23648812 | 0.83 | NR5A1 (0.56) | ALDH1A1NPC1TP53RAB9ANR5A1 | |
| SCHEMBL8030985 | 0.83 | NR5A1 (0.56) | ALDH1A1NPC1TP53RAB9ANR5A1 | |
| SCHEMBL28930709 | 0.83 | PRMT1 (0.40) | GAAPRMT1F2ST14HRH3 | |
| SCHEMBL5441253 | 0.83 | NR5A1 (0.56) | ALDH1A1NPC1TP53RAB9ANR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004050-B1 | CYANOSTILBENES | ROLIC TECH AG (CH) | 2020-09-02 | — | — | EP | disclosed |
| EP-3004050-B1 | CYANOSTILBENES | ROLIC TECH AG (CH) | 2020-09-02 | — | — | EP | disclosed |
| CN-111533668-A | Cyanostilbenes | 罗利克技术有限公司 | 2020-08-14 | — | — | CN | disclosed |
| US-10329486-B2 | Cyanostilbenes | ROLIC AG (CH) | 2019-06-25 | — | — | US | disclosed |
| US-10329486-B2 | Cyanostilbenes | ROLIC AG (CH) | 2019-06-25 | — | — | US | disclosed |
| EP-2748280-B1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2016-11-30 | — | — | EP | disclosed |
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| EP-3004050-A1 | CYANOSTILBENES | Rolic AG (CH) | 2016-04-13 | — | — | EP | disclosed |
| US-20160083655-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2016-03-24 | — | — | US | disclosed |
| US-20160083655-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2016-03-24 | — | — | US | disclosed |
| US-20160083655-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2016-03-24 | — | — | US | disclosed |
| WO-2014191292-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2014-12-04 | — | — | WO | disclosed |
| WO-2014191292-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2014-12-04 | — | — | WO | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
| EP-2748280-A1 | PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026691-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | PCNA, CRY1, CRY2 | MEN1 2468/4885KMT2A 2475/4885USP2 3477/4885 |
| US-20160083655-A1 | CYANOSTILBENES | LATS1, LATS2, CRY1 | MEN1 4064/4885KMT2A 2902/4885USP2 2395/4885 |
| US-10329486-B2 | Cyanostilbenes | LATS1, LATS2, CRY1 | MEN1 4064/4885KMT2A 2902/4885USP2 2395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.