Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722777 | 0.85 | GPR119 (0.34) | GPR119 | |
| SCHEMBL14722673 | 0.82 | GPR119 (0.39) | GPR119 | |
| SCHEMBL14723276 | 0.80 | GPR119 (0.33) | GPR119MAPT | |
| SCHEMBL457723 | 0.73 | NTRK1 (0.34) | NTRK1 | |
| SCHEMBL459944 | 0.72 | NTRK1 (0.34) | NTRK1 | |
| SCHEMBL459071 | 0.71 | NTRK1 (0.33) | MAPTNTRK1 | |
| SCHEMBL457491 | 0.69 | ITGB3 (0.34) | NTRK1 | |
| SCHEMBL460033 | 0.68 | RET (0.33) | GPR119NTRK1 | |
| SCHEMBL14730179 | 0.68 | GPR119 (0.34) | GPR119NTRK1 | |
| SCHEMBL14730227 | 0.67 | NTRK1 (0.34) | GPR119NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |