Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458010 | 0.92 | ITGB3 (0.34) | ITGB3ITGA2BFPR2DHODHCHEK2 | |
| SCHEMBL460033 | 0.89 | RET (0.33) | NTRK1RORC | |
| SCHEMBL459944 | 0.84 | NTRK1 (0.34) | NTRK1RORC | |
| SCHEMBL457723 | 0.84 | NTRK1 (0.34) | NTRK1RORC | |
| SCHEMBL459071 | 0.81 | NTRK1 (0.33) | NTRK1RORC | |
| SCHEMBL459362 | 0.80 | — | — | |
| SCHEMBL457628 | 0.80 | GPR119 (0.34) | CHEK2 | |
| SCHEMBL463438 | 0.79 | HTR2A (0.35) | — | |
| SCHEMBL14722673 | 0.73 | GPR119 (0.39) | — | |
| SCHEMBL463286 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |