Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14724517 | 0.82 | RAB9A (0.49) | MAPK1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL14714633 | 0.76 | PLK1 (0.40) | SMN1; SMN2RAB9AMAPTTSHRGAA | |
| SCHEMBL8173029 | 0.76 | CNR2 (0.48) | TSHRPKM | |
| SCHEMBL664126 | 0.76 | TSHR (0.41) | TSHRPKM | |
| SCHEMBL8920815 | 0.75 | LMNA (0.50) | SMN1; SMN2MAPTLMNA | |
| SCHEMBL14786715 | 0.72 | TAS1R3 (0.43) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL14786670 | 0.72 | CFTR (0.41) | NPC1RAB9AKMT2AMAPTLMNA | |
| SCHEMBL2925457 | 0.71 | PTPRB (0.42) | KMT2AMAPTTSHRMEN1PKM | |
| SCHEMBL18831936 | 0.71 | TSHR (0.43) | MAPK1LMNATSHR | |
| SCHEMBL27745010 | 0.71 | POLB (0.47) | NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562155-A1 | NOVEL HYDROXAMIC ACID DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2013-02-27 | — | — | EP | disclosed |