Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920815 | 0.80 | LMNA (0.50) | POLBTRPV1TPMTHTTCA1 | |
| SCHEMBL27794162 | 0.79 | CA2 (0.60) | MAOBCA1CA2 | |
| SCHEMBL4298025 | 0.78 | PLK1 (0.59) | POLBAOC3MAOBNPC1RAB9A | |
| SCHEMBL27754575 | 0.73 | CYP2D6 (0.45) | POLBHTTNPC1RAB9AATM | |
| SCHEMBL1363640 | 0.73 | MPO (0.64) | TRPV1TPMTCA1CA2LMNA | |
| SCHEMBL27745007 | 0.72 | CYP1A2 (0.44) | TRPV1NPC1RAB9ALMNA | |
| SCHEMBL16346440 | 0.71 | TRPV1 (0.41) | POLBTRPV1TPMTNPC1RAB9A | |
| SCHEMBL14724481 | 0.71 | MAPK1 (0.41) | NPC1RAB9ALMNA | |
| SCHEMBL16346499 | 0.71 | TRPV1 (0.38) | POLBTRPV1TPMTHTTNPC1 | |
| SCHEMBL10896464 | 0.71 | HDAC1 (0.54) | NPC1RAB9AHDAC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472916-A | Chemical compounds | ASTRAZENECA AB (SE) | 2009-07-01 | — | — | CN | disclosed |