SCHEMBL14725231

SCHEMBL14725231

c1ccc(-c2cc(-c3cccc4ccccc34)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
ALDH1A1 P00352 5/20 0.54
HPGD P15428 5/20 0.54
KDM4E B2RXH2 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
TDP1 Q9NUW8 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MAPK1 P28482 2/20 0.54
TP53 P04637 1/20 0.54
TSHR P16473 1/20 0.54
NFKB1 P19838 1/20 0.54
NFKB2 Q00653 1/20 0.54
RELA Q04206 1/20 0.54
ATM Q13315 1/20 0.54
HSD17B10 Q99714 1/20 0.54
MEN1 O00255 8/20 0.53
KMT2A Q03164 8/20 0.53
NTSR1 P30989 1/20 0.53
LMNA P02545 3/20 0.50
ADORA2A P29274 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12306181 0.97 MEN1 (0.54) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL10051210 0.97 MEN1 (0.54) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL10051293 0.97 MEN1 (0.54) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL10051196 0.97 MEN1 (0.54) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL12306184 0.96 ALDH1A1 (0.57) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL17969914 0.96 ALDH1A1 (0.57) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL17969997 0.95 MEN1 (0.53) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL27101215 0.95 MEN1 (0.50) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL18818820 0.95 MEN1 (0.53) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL17969950 0.95 MEN1 (0.53) MAPTALDH1A1HPGDKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026217-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-01-25 US disclosed
US-20240026217-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-01-25 US disclosed
US-11773321-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-03 US disclosed
US-11773321-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-03 US disclosed
US-20210277305-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-09-09 US disclosed
US-11008510-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-05-18 US disclosed
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same LG CHEM, LTD. 2021-02-02 US disclosed
EP-3345982-B1 DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEMICAL LTD (KR) 2020-03-18 EP disclosed
CN-108409672-B Method for synthesizing polysubstituted pyrimidine under catalysis of copper salt 安徽师范大学 2020-01-10 CN disclosed
CN-108409672-A A kind of method that mantoquita catalyzes and synthesizes polysubstituted pyrimidine 安徽师范大学 2018-08-17 CN disclosed
US-20170253796-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-07 US disclosed
US-20170253796-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-07 US disclosed
US-20170244044-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-24 US disclosed
US-20170244044-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-24 US disclosed
US-9663711-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-30 US disclosed
US-9663711-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-30 US disclosed
WO-2017061810-A1 DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2017-04-13 WO disclosed
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2013-02-28 US disclosed
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2013-02-28 US disclosed
WO-2013027846-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, LIGHTING DEVICE, AND NOVEL ORGANIC COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same NR2E3, ALDH1A2, CRY1 MAPT 1561/4885ALDH1A1 35/4885HPGD 2182/4885
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound LAGE3, LEF1, PUM2 MAPT 2505/4885ALDH1A1 813/4885HPGD 3070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.