SCHEMBL14725274

SCHEMBL14725274

c1cc(-c2cc(-c3cccc(-c4cc5ccccc5c5ccccc45)c3)ncn2)cc(-c2cccc3ccccc23)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.46
ALDH1A1 P00352 4/20 0.41
HPGD P15428 3/20 0.41
HSD17B10 Q99714 3/20 0.41
TSHR P16473 2/20 0.41
MAPK1 P28482 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HIF1A Q16665 2/20 0.41
CASP1 P29466 1/20 0.41
KMO O15229 1/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
MPI P34949 1/20 0.39
KMT2A Q03164 1/20 0.39
MCL1 Q07820 2/20 0.38
ACMSD Q8TDX5 1/20 0.38
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14718746 0.95 CYP11B1 (0.50) CYP11B1ALDH1A1HPGDHSD17B10TSHR
SCHEMBL29362973 0.95 CYP11B1 (0.50) CYP11B1ALDH1A1HPGDHSD17B10TSHR
SCHEMBL14725247 0.94 CYP11B1 (0.49) CYP11B1ALDH1A1HPGDHSD17B10TSHR
SCHEMBL14725263 0.92 KMO (0.45) ALDH1A1HPGDHSD17B10TSHRMAPK1
SCHEMBL14725245 0.84 CYP11B1 (0.49) CYP11B1ALDH1A1HPGDTSHRL3MBTL1
SCHEMBL19271387 0.84 ALDH1A1 (0.44) CYP11B1ALDH1A1HPGDHSD17B10TSHR
SCHEMBL19763084 0.84 ENPP3 (0.45) CYP11B1ALDH1A1HPGDHSD17B10TSHR
SCHEMBL14725266 0.84 FNTA (0.44) ALDH1A1HPGDHSD17B10TSHRMAPK1
SCHEMBL17539809 0.83 ALDH1A1 (0.43) CYP11B1ALDH1A1HPGDHSD17B10TSHR
SCHEMBL17539799 0.83 ALDH1A1 (0.47) CYP11B1ALDH1A1HPGDHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026217-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-01-25 US disclosed
US-20240026217-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-01-25 US disclosed
US-11773321-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-03 US disclosed
US-11773321-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-03 US disclosed
US-20210277305-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-09-09 US disclosed
US-11008510-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-05-18 US disclosed
US-20170253796-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-07 US disclosed
US-20170253796-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-07 US disclosed
US-9663711-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-30 US disclosed
US-9663711-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-30 US disclosed
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2013-02-28 US disclosed
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2013-02-28 US disclosed
WO-2013027846-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, LIGHTING DEVICE, AND NOVEL ORGANIC COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound LAGE3, LEF1, PUM2 CYP11B1 3844/4885ALDH1A1 813/4885HPGD 3070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.