Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 3/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24990754 | 0.85 | TP53BP1 (0.55) | TP53BP1HDAC1HDAC2MTORGRM5 | |
| SCHEMBL2291348 | 0.83 | TP53BP1 (0.57) | TP53BP1HDAC1HDAC2MTORGRM5 | |
| SCHEMBL8298056 | 0.81 | KDM4E (0.53) | HDAC1SPHK2F2MRGPRX4GAA | |
| SCHEMBL2293623 | 0.80 | ALDH1A1 (0.63) | TP53BP1HDAC1HDAC2MTORGRM5 | |
| SCHEMBL14725929 | 0.80 | SPHK2 (0.47) | HDAC2SPHK2MRGPRX4GAAKMT2A | |
| SCHEMBL23714782 | 0.80 | HDAC8 (0.59) | KMT2ASMN1; SMN2 | |
| SCHEMBL13331944 | 0.80 | PARP1 (0.58) | KMT2AALDH1A1 | |
| SCHEMBL13381540 | 0.79 | TP53BP1 (0.60) | TP53BP1HDAC1HDAC2MTORGRM5 | |
| Hydrochloric Acid SCHEMBL7760549 | 0.79 | TP53BP1 (0.59) | TP53BP1HDAC1HDAC2SPHK2MTOR | |
| SCHEMBL3090568 | 0.78 | GAA (0.63) | HDAC1HDAC2SPHK2GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130052132-A1 | Method for Producing Radioactively Labeled Polypeptide | ARKRAY, INC. (JP) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130052132-A1 | Method for Producing Radioactively Labeled Polypeptide | XPNPEP2, ARGLU1, XPNPEP1 | TP53BP1 2386/4885HDAC1 1648/4885HDAC2 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.