SCHEMBL14726869

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3465721	0.85	ACHE (0.50)	ACHEESR2ESR1HTTMAPT
	SCHEMBL15116969	0.85	AHR (0.52)	ACHEESR2ESR1AHRCYP2A6
	SCHEMBL14726974	0.83	ACHE (0.46)	ACHEAHRCYP2A6CYP1A2HTT
	SCHEMBL29416110	0.82	ESR1 (0.53)	ESR2ESR1CYP1A2MAPTLMNA
	SCHEMBL574096	0.82	ESR1 (0.53)	ESR2ESR1CYP1A2MAPTLMNA
	SCHEMBL22512513	0.82	CYP2A6 (0.50)	ACHEESR2ESR1CYP2A6CYP1A2
	SCHEMBL36757	0.82	ACHE (0.56)	ACHEESR2ESR1HTTMAPT
	SCHEMBL29354925	0.82	ACHE (0.56)	ACHEESR2ESR1HTTMAPT
	SCHEMBL25677354	0.81	ACHE (0.38)	ACHEESR2ESR1CYP2A6CYP1A2
	SCHEMBL9971795	0.80	MAOA (0.48)	ACHEESR2ESR1CYP2A6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.