SCHEMBL14726974

SCHEMBL14726974

Cc1ccc(-c2c3ccccc3c(-c3ccc(C)cc3)c3cc(Cl)c(Cl)cc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.46
ALDH1A1 P00352 4/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HPGD P15428 2/20 0.42
MAPT P10636 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAOB P27338 2/20 0.38
RAB9A P51151 2/20 0.38
TNKS O95271 1/20 0.38
PARP1 P09874 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
PARP2 Q9UGN5 1/20 0.38
GRM5 P41594 1/20 0.38
CTSV O60911 1/20 0.38
CTSL P07711 1/20 0.38
GSK3B P49841 1/20 0.37
ADK P55263 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3477351 0.85 ACHE (0.57) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL30742831 0.85 ACHE (0.57) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL5843363 0.85 ACHE (0.44) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL12415331 0.83 ACHE (0.49) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL14726869 0.83 ACHE (0.43) ACHEKDM4EL3MBTL1MAPTTDP1
SCHEMBL30924193 0.81 ACHE (0.58) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL21224502 0.81 ACHE (0.58) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL14726990 0.79 HSD11B1 (0.40) ALDH1A1L3MBTL1RAB9ATNKSTNKS2
SCHEMBL24688385 0.79 ACHE (0.56) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL3722164 0.76 ACHE (0.48) ACHEALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8859112-B2 Organic compound and organic light emitting element using the same CANON KABUSHIKI KAISHA (JP) 2014-10-14 US disclosed
US-8859112-B2 Organic compound and organic light emitting element using the same CANON KABUSHIKI KAISHA (JP) 2014-10-14 US disclosed
US-20130049581-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-02-28 US disclosed
US-20130049581-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130049581-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME LEF1, CYP1A1, TCF7L2 ACHE 3578/4885ALDH1A1 107/4885KDM4E 2992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.