Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPR3 | P17342 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728212 | 0.86 | LDHA (0.44) | PREPCA12CA1CA9ITGB3 | |
| SCHEMBL14728208 | 0.83 | LTA4H (0.44) | PREPADRB3ITGB3ITGA2BATM | |
| SCHEMBL10656495 | 0.79 | ATM (0.51) | CA12CA1ATMITGA4ITGB7 | |
| SCHEMBL642059 | 0.79 | ATM (0.51) | CA12CA1ATMITGA4ITGB7 | |
| SCHEMBL28736964 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BATMACACBCTSS | |
| SCHEMBL28736965 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BATMACACBCTSS | |
| SCHEMBL20437145 | 0.79 | ITGB3 (0.52) | ITGB3ITGA2BITGA4ITGB7LMNA | |
| SCHEMBL9848674 | 0.78 | CYP1A2 (0.47) | PREPCA12CA1CA9LDHA | |
| SCHEMBL13080680 | 0.78 | PREP (0.42) | PREPCA12CA1CA9LDHA | |
| SCHEMBL7588471 | 0.78 | PREP (0.42) | PREPCA12CA1CA9ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230131121-A1 | BRANCHED DISCRETE PEG CONSTRUCTS | AUDAX PRIVATE DEBT LLC, AS AGENT | 2023-04-27 | — | — | US | disclosed |
| US-20170313656-A1 | Branched Discrete PEG Constructs | QUANTA BIODESIGN, LTD. | 2017-11-02 | — | — | US | disclosed |
| US-20150065711-A1 | Discrete PEG Constructs | EQUIP, LLC (US) | 2015-03-05 | — | — | US | disclosed |
| US-20130052130-A1 | Branched Discreet PEG Constructs | UNIVERSITY OF WASHINGTON (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313656-A1 | Branched Discrete PEG Constructs | BTD, IDUA, DNPEP | PREP 179/4885CA12 130/4885CA1 1425/4885 |
| US-20150065711-A1 | Discrete PEG Constructs | MUC1, EGFR, LNPEP | PREP 817/4885CA12 712/4885CA1 2212/4885 |
| US-20230131121-A1 | BRANCHED DISCRETE PEG CONSTRUCTS | BTD, IDUA, DNPEP | PREP 160/4885CA12 132/4885CA1 1416/4885 |
| US-20130052130-A1 | Branched Discreet PEG Constructs | BTD, DNPEP, IDUA | PREP 102/4885CA12 91/4885CA1 1384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.