Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891444 | 0.85 | MASP2 (0.45) | ALDH1A1TDP1LMNAMAOBMASP2 | |
| SCHEMBL14732011 | 0.79 | NPC1 (0.31) | CYP1A2NPC1 | |
| SCHEMBL14732007 | 0.78 | AR (0.31) | PDK2 | |
| SCHEMBL14732006 | 0.74 | PTPN5 (0.36) | PDK2 | |
| SCHEMBL8907017 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNAMAOBGABRA1 | |
| SCHEMBL4375599 | 0.70 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNAMAOBGAA | |
| SCHEMBL10449096 | 0.69 | ALDH1A1 (0.51) | ALDH1A1TDP1GAAMAPK1MEN1 | |
| SCHEMBL24710396 | 0.68 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNAGAACYP3A4 | |
| SCHEMBL2106091 | 0.68 | ALDH1A1 (0.35) | ALDH1A1TDP1LMNAMAOBGAA | |
| SCHEMBL24711415 | 0.67 | TDP1 (0.50) | ALDH1A1TDP1LMNACYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389766-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |