Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 17/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 17/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376266 | 0.80 | FEN1 (0.42) | LPAR1LPAR5FEN1 | |
| SCHEMBL14732137 | 0.78 | LPAR1 (0.44) | LPAR1LPAR5 | |
| SCHEMBL14732192 | 0.77 | SRD5A2 (0.60) | LPAR1LPAR5 | |
| SCHEMBL3130872 | 0.69 | TTR (0.68) | LPAR1LPAR5 | |
| SCHEMBL5156190 | 0.69 | LMNA (0.68) | — | |
| SCHEMBL3376339 | 0.68 | PTGES (0.58) | LPAR1LPAR5 | |
| SCHEMBL21628551 | 0.67 | LMNA (0.56) | LPAR1LPAR5 | |
| SCHEMBL14732180 | 0.66 | NR3C1 (0.50) | — | |
| SCHEMBL16506848 | 0.66 | LPAR1 (1.00) | LPAR1LPAR5 | |
| SCHEMBL16507486 | 0.65 | LPAR1 (1.00) | LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389500-B2 | Fused heterocyclic compounds as ion channel modulators | GILEAD SCIENCES, INC. (US) | 2013-03-05 | — | — | US | claimed |