SCHEMBL14734294

SCHEMBL14734294

CCN1CC(c2ccccc2)OC1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FADS1 O60427 3/20 0.53
DDB1 Q16531 1/20 0.46
CRBN Q96SW2 1/20 0.46
ADORA3 P0DMS8 2/20 0.45
LMNA P02545 1/20 0.45
HTR6 P50406 1/20 0.45
GRM2 Q14416 2/20 0.42
HSD11B1 P28845 2/20 0.42
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CETP P11597 2/20 0.41
ROCK2 O75116 1/20 0.40
ROCK1 Q13464 1/20 0.40
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KDM4E B2RXH2 1/20 0.39
AR P10275 1/20 0.39
CYP19A1 P11511 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13547539 1.00 FADS1 (0.53) FADS1DDB1CRBNADORA3LMNA
SCHEMBL13413433 1.00 FADS1 (0.53) FADS1DDB1CRBNADORA3LMNA
SCHEMBL3484313 0.84 FADS1 (0.54) FADS1GRM2
SCHEMBL13413561 0.84 GRM2 (0.45) FADS1DDB1CRBNLMNAHTR6
SCHEMBL15689305 0.83 FADS1 (0.56) FADS1DDB1CRBNADORA3HTR6
SCHEMBL13413432 0.82 CYP2A6 (0.48) FADS1GRM2MAPK1NPSR1KDM4E
SCHEMBL13413437 0.82 HTR6 (0.52) FADS1HTR6GRM2
SCHEMBL2913770 0.82 FADS1 (0.56) FADS1GRM2
SCHEMBL22623657 0.82 MAPK1 (0.53) FADS1DDB1CRBNGRM2MAPK1
SCHEMBL2913774 0.82 FADS1 (0.56) FADS1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110152473-B Gold nano-loaded trisulfide thiocyanate absorbent and preparation method thereof 东北大学 2021-05-28 CN disclosed
US-20130053372-A1 5-HT RECEPTOR MODULATORS CAMBRIDGE ENTERPRISE LIMITED 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130053372-A1 5-HT RECEPTOR MODULATORS HTR1B, HTR5A, HTR1A FADS1 3090/4885DDB1 3751/4885CRBN 2731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.