Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27408052 | 0.97 | DNM1 (0.48) | DNM1KDM4EPMP22ATMALDH1A1 | |
| SCHEMBL272419 | 0.97 | DNM1 (0.52) | DNM1KDM4EPMP22ATMALDH1A1 | |
| Bromide SCHEMBL7214859 | 0.94 | DNM1 (0.55) | DNM1KDM4EPMP22ATMALDH1A1 | |
| Iodide SCHEMBL14777716 | 0.94 | DNM1 (0.50) | DNM1KDM4EPMP22ATMALDH1A1 | |
| Water SCHEMBL319990 | 0.94 | DNM1 (0.50) | DNM1KDM4EPMP22ATMALDH1A1 | |
| Hydrochloric Acid SCHEMBL9003642 | 0.92 | DNM1 (0.44) | DNM1KDM4EPMP22ATMALDH1A1 | |
| SCHEMBL11706247 | 0.91 | DNM1 (0.46) | DNM1KDM4EPMP22ATMALDH1A1 | |
| Water SCHEMBL3308247 | 0.88 | DNM1 (0.43) | DNM1KDM4EPMP22ATMALDH1A1 | |
| SCHEMBL1686201 | 0.88 | DNM1 (0.57) | DNM1ALDH1A1TSHRSLC22A1SLC22A2 | |
| SCHEMBL10600603 | 0.86 | DNM1 (0.62) | DNM1ALDH1A1TSHRSLC22A1SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114737200-B | Dechlorination and corrosion inhibition method for iron articles | 国家纳米科学中心 | 2024-05-28 | — | — | CN | claimed |
| CN-114737200-A | Dechlorination and corrosion inhibition method for iron object | 国家纳米科学中心 | 2022-07-12 | — | — | CN | claimed |
| CN-108486930-A | The method for sorting of the cation-modified reactive dyeing of single bath process | 东华大学 | 2018-09-04 | — | — | CN | claimed |
| CN-108162112-A | A kind of ternary built dyestuff and the method that high color fastness veneer layer is prepared using the dyestuff | 德华兔宝宝装饰新材股份有限公司 | 2018-06-15 | — | — | CN | claimed |
| CN-104530248-A | Production method of cassava modified starch | GUANGDONG FONTI BIOCHEMICAL TECHNOLOGY CO LTD | 2015-04-22 | — | — | CN | claimed |
| CN-114737200-B | Dechlorination and corrosion inhibition method for iron articles | 国家纳米科学中心 | 2024-05-28 | — | — | CN | disclosed |
| CN-114737200-A | Dechlorination and corrosion inhibition method for iron object | 国家纳米科学中心 | 2022-07-12 | — | — | CN | disclosed |
| CN-105666619-B | A kind of oriented wood chipboard | 德华兔宝宝装饰新材股份有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-105563586-B | A kind of preparation method of functional form Recombinant Wood | 德华兔宝宝装饰新材股份有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-105461873-B | A kind of recombinant decorative material Recombinant Wood | 德华兔宝宝装饰新材股份有限公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-108162112-A | A kind of ternary built dyestuff and the method that high color fastness veneer layer is prepared using the dyestuff | 德华兔宝宝装饰新材股份有限公司 | 2018-06-15 | — | — | CN | disclosed |
| CN-105619565-B | A kind of fire-retardant oriented wood chipboard | 德华兔宝宝装饰新材股份有限公司 | 2018-04-13 | — | — | CN | disclosed |
| CN-104530248-A | Production method of cassava modified starch | GUANGDONG FONTI BIOCHEMICAL TECHNOLOGY CO LTD | 2015-04-22 | — | — | CN | disclosed |
| US-8658842-B2 | Process for producing ethylene glycol catalyzed by ionic liquid | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2014-02-25 | — | — | US | disclosed |
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2013-03-21 | — | — | US | disclosed |
| EP-2563818-A1 | CASSIA DERIVATIVES | Lubrizol Advanced Materials, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | AGL, ALKBH3, ELL | DNM1 2294/4885KDM4E 1534/4885PMP22 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.