Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29845663 | 0.79 | METAP1 (0.51) | CYP3A4KMT2ADHODHKDM4EMETAP1 | |
| SCHEMBL29660606 | 0.78 | METAP2 (0.54) | METAP2CYP3A4PIM1RAD52KMT2A | |
| SCHEMBL321962 | 0.78 | METAP2 (0.54) | METAP2CYP3A4PIM1RAD52KMT2A | |
| SCHEMBL28472391 | 0.77 | MEN1 (0.51) | METAP2CYP3A4PIM1KMT2AADORA2A | |
| SCHEMBL30494436 | 0.77 | MEN1 (0.51) | METAP2CYP3A4PIM1KMT2AADORA2A | |
| SCHEMBL27333822 | 0.76 | KDM4E (0.45) | METAP2CYP3A4PIM1KMT2AKDM4E | |
| SCHEMBL24590231 | 0.74 | PIM1 (0.45) | METAP2CYP3A4PIM1KMT2AADORA2A | |
| SCHEMBL7962384 | 0.74 | CYP3A4 (0.57) | METAP2CYP3A4PIM1KMT2AADORA2A | |
| SCHEMBL4512439 | 0.73 | NPC1 (0.50) | KMT2AADORA2AKDM4EGPR3 | |
| SCHEMBL8149733 | 0.72 | KMT2A (0.49) | CYP3A4RAD52KMT2ADHODHACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564851-B1 | Agent exhibiting the properties of a cognitive function promoter | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTJU UNIKORM (RU) | 2014-06-11 | — | — | EP | disclosed |
| US-8476433-B2 | Agent exhibiting the properties of a cognitive function promoter (embodiments) | UNIKORM (RU) | 2013-07-02 | — | — | US | disclosed |
| US-20130131342-A1 | AGENT EXHIBITING THE PROPERTIES OF A COGNITIVE FUNCTION PROMOTER (EMBODIMENTS) | UNIKORM (RU) | 2013-05-23 | — | — | US | disclosed |
| EP-2564851-A2 | AGENT EXHIBITING THE PROPERTIES OF A COGNITIVE FUNCTION PROMOTER (EMBODIMENTS) | Obschestvo S Ogranichennoi Otvetstvennostju "Unikorm" (RU) | 2013-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131342-A1 | AGENT EXHIBITING THE PROPERTIES OF A COGNITIVE FUNCTION PROMOTER (EMBODIMENTS) | BDNF, TET1, PNMT | METAP2 1086/4885CYP3A4 895/4885PIM1 3153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.