Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.30 |
| ▸ | CCR3 | P51677 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831288 | 0.81 | LMNA (0.30) | — | |
| SCHEMBL701917 | 0.77 | SIGMAR1 (0.35) | — | |
| SCHEMBL28108702 | 0.74 | HSD17B10 (0.50) | — | |
| SCHEMBL7142589 | 0.71 | KMT2A (0.42) | HRH3 | |
| SCHEMBL16607424 | 0.71 | SLC6A9 (0.42) | — | |
| SCHEMBL27315681 | 0.71 | SLC6A9 (0.42) | — | |
| SCHEMBL31031052 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL864305 | 0.67 | GRIN2D (0.35) | HRH3KCNH2 | |
| SCHEMBL27699380 | 0.66 | SIGMAR1 (0.41) | HRH3ALOX5KCNH2 | |
| SCHEMBL4342319 | 0.65 | LTA4H (0.36) | HRH3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099788-B1 | CYCLICALLY SUBSTITUTED 3,5-DICYANO-2-THIOPYRIDINES AND USE THEREOF | BAYER IP GMBH (DE) | 2013-03-06 | — | — | EP | disclosed |