Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14735933 | 1.00 | HSD11B1 (0.46) | HSD11B1ALDH1A1KMT2AMAPTPLA2G1B | |
| SCHEMBL14752298 | 0.89 | ERN1 (0.40) | ALDH1A1NPC1RAB9ACYP2A6ERN1 | |
| SCHEMBL3094017 | 0.85 | ALDH1A1 (0.59) | HSD11B1ALDH1A1KMT2AMAPTPOLB | |
| SCHEMBL3094031 | 0.85 | ALDH1A1 (0.59) | HSD11B1ALDH1A1KMT2AMAPTPOLB | |
| SCHEMBL25540386 | 0.85 | ALDH1A1 (0.41) | HSD11B1ALDH1A1KMT2AMAPTPLA2G1B | |
| SCHEMBL2566801 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPTPLA2G1BPOLB | |
| SCHEMBL14752307 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPTPLA2G1BPOLB | |
| SCHEMBL2566805 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPTPLA2G1BPOLB | |
| SCHEMBL14752283 | 0.81 | HSD11B1 (0.54) | HSD11B1KMT2AMAPTNFE2L2MEN1 | |
| SCHEMBL1751871 | 0.80 | HSD11B1 (0.62) | HSD11B1ALDH1A1KMT2ANFE2L2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059996-A1 | Boron-Containing PI-Electron Materials Incorporating Formally Aromatic and Neutral Borepin Rings | THE JOHNS HOPKINS UNIVERSITY | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059996-A1 | Boron-Containing PI-Electron Materials Incorporating Formally Aromatic and Neutral Borepin Rings | PNN, CIAPIN1, VNN1 | HSD11B1 3340/4885ALDH1A1 4476/4885KMT2A 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.