Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875149 | 0.85 | TDP1 (0.48) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL575472 | 0.81 | CYP2C9 (0.32) | CYP2C9 | |
| SCHEMBL3822561 | 0.79 | LMNA (0.38) | TSHRCHRM2CHRM4CHRM1LMNA | |
| SCHEMBL28292460 | 0.78 | TDP1 (0.43) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL1698005 | 0.78 | TSHR (0.48) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL1232896 | 0.78 | TSHR (0.48) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL12175911 | 0.76 | TDP1 (0.42) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL7539461 | 0.76 | TSHR (0.46) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL15261665 | 0.76 | TSHR (0.46) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL362428 | 0.76 | TSHR (0.46) | TDP1TSHRTRPV1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986310-A | Novel compound, namely rubusoside B, and preparation method and application thereof | 湖南中医药大学 | 2024-05-07 | — | — | CN | claimed |
| CN-115650913-B | Quinone quinoline compound and preparation method and application thereof | 北京中医药大学 | 2024-03-01 | — | — | CN | claimed |
| CN-112538016-B | Method for extracting chlorogenic acid n-butyl ester from peach blossom | 黄河科技学院 | 2023-03-10 | — | — | CN | claimed |
| CN-113461747-B | 2 compounds with hypoglycemic activity in rose hip | 吉林化工学院 | 2023-02-03 | — | — | CN | claimed |
| CN-115650913-A | Quinoid quinoline compound and preparation method and application thereof | 北京中医药大学 | 2023-01-31 | — | — | CN | claimed |
| CN-115518096-A | Integrated comprehensive extraction and separation method for effective components of epimedium | 李玉山 | 2022-12-27 | — | — | CN | claimed |
| CN-115350177-A | Uric acid reducing function of extract and preparation method thereof | 暨南大学 | 2022-11-18 | — | — | CN | claimed |
| CN-115015418-A | Quality detection method for Japanese ardisia herb decoction | 湖南新汇制药股份有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-113773361-A | Compound for treating hyperuricemia, composition thereof, preparation method and medical application | 深圳弘汇生物医药有限公司 | 2021-12-10 | — | — | CN | claimed |
| CN-113461747-A | New compound with hypoglycemic activity in 2 rosa davurica fruits and preparation method thereof | 吉林化工学院 | 2021-10-01 | — | — | CN | claimed |
| EP-3255031-B1 | COMPOUND, AND SEPARATION METHOD, SYNTHESIS METHOD AND USE THEREOF | BEIJING PEKING UNIV WBL BIOTECH CO LTD (CN) | 2021-09-29 | — | — | EP | claimed |
| CN-107207404-B | Compound, and separation method, synthesis method and application thereof | 北京北大维信生物科技有限公司 | 2021-07-13 | — | — | CN | claimed |
| CN-112624928-A | Anticoagulant peach blossom effective component and application thereof | 黄河科技学院 | 2021-04-09 | — | — | CN | claimed |
| CN-112538016-A | Method for extracting chlorogenic acid n-butyl ester from peach blossom | 黄河科技学院 | 2021-03-23 | — | — | CN | claimed |
| CN-107556358-B | Effective component of procoagulant cordyceps militaris and extraction and separation method and application thereof | 黄河科技学院 | 2019-08-23 | — | — | CN | claimed |
| US-10099998-B2 | Compound, and separation method, synthesis method and use thereof | BEIJING PEKING UNIVERSITY WBL BIOTECH CO., LTD. (CN) | 2018-10-16 | — | — | US | claimed |
| US-20180022688-A1 | COMPOUND, AND SEPARATION METHOD, SYNTHESIS METHOD AND USE THEREOF | BEIJING PEKING UNIVERSITY WBL BIOTECH CO., LTD. (CN) | 2018-01-25 | — | — | US | claimed |
| CN-101057895-B | 'Fuyanshu' preparation for treating gynopathy and its quality controlling method | BEIJING QIYUAN YIDE INST OF MATERIA MEDICA | 2010-05-19 | — | — | CN | claimed |
| CN-101057895-A | 'Fuyanshu' preparation for treating gynopathy and its preparation method and quality controlling method and application | QIYUANYIDE MEDICINES INST BEIJ (CN) | 2007-10-24 | — | — | CN | claimed |
| CN-117986310-A | Novel compound, namely rubusoside B, and preparation method and application thereof | 湖南中医药大学 | 2024-05-07 | — | — | CN | disclosed |
| CN-115650913-B | Quinone quinoline compound and preparation method and application thereof | 北京中医药大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-117538475-A | Thin layer detection method and identification method for lily medicinal material primordium | 华润三九现代中药制药有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-115015418-B | Quality detection method of Japanese ardisia herb decoction | 湖南新汇制药股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-116953144-A | Thin-layer chromatography identification method of Dan-zedoary Fukang decoction | 云南圣科药业有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-112724183-B | Preparation method of arctiin | 蚌埠学院 | 2023-08-22 | — | — | CN | disclosed |
| US-20230233694-A1 | ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | IMMUNOMEDICS, INC. | 2023-07-27 | — | — | US | disclosed |
| CN-115350177-B | Uric acid reducing function of extract and preparation method thereof | 暨南大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-113577090-B | Application of arctiin in preparation of prostatic hyperplasia medicine | 上海交通大学医学院附属第九人民医院 | 2023-04-25 | — | — | CN | disclosed |
| CN-112624928-B | Anticoagulant peach blossom effective component and application thereof | 黄河科技学院 | 2023-03-17 | — | — | CN | disclosed |
| CN-112645996-B | Peach blossom effective component for promoting coagulation and extraction and separation method and application thereof | 黄河科技学院 | 2023-03-17 | — | — | CN | disclosed |
| CN-112624928-B | Anticoagulant peach blossom effective component and application thereof | 黄河科技学院 | 2023-03-17 | — | — | CN | disclosed |
| CN-112538016-B | Method for extracting chlorogenic acid n-butyl ester from peach blossom | 黄河科技学院 | 2023-03-10 | — | — | CN | disclosed |
| CN-112538016-B | Method for extracting chlorogenic acid n-butyl ester from peach blossom | 黄河科技学院 | 2023-03-10 | — | — | CN | disclosed |
| CN-113461747-B | 2 compounds with hypoglycemic activity in rose hip | 吉林化工学院 | 2023-02-03 | — | — | CN | disclosed |
| CN-115650913-A | Quinoid quinoline compound and preparation method and application thereof | 北京中医药大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-115518096-A | Integrated comprehensive extraction and separation method for effective components of epimedium | 李玉山 | 2022-12-27 | — | — | CN | disclosed |
| CN-115350177-A | Uric acid reducing function of extract and preparation method thereof | 暨南大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-115015418-A | Quality detection method for Japanese ardisia herb decoction | 湖南新汇制药股份有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-113773361-B | Compound for treating hyperuricemia, composition thereof, preparation method and medical application | 深圳弘汇生物医药有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-113848278-A | Quality control method for standard decoction of radix Cudraniae | 湖南新汇制药股份有限公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-113773361-A | Compound for treating hyperuricemia, composition thereof, preparation method and medical application | 深圳弘汇生物医药有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-113577090-A | Application of arctiin in preparation of prostatic hyperplasia drugs | 上海交通大学医学院附属第九人民医院 | 2021-11-02 | — | — | CN | disclosed |
| CN-113461747-A | New compound with hypoglycemic activity in 2 rosa davurica fruits and preparation method thereof | 吉林化工学院 | 2021-10-01 | — | — | CN | disclosed |
| EP-3255031-B1 | COMPOUND, AND SEPARATION METHOD, SYNTHESIS METHOD AND USE THEREOF | BEIJING PEKING UNIV WBL BIOTECH CO LTD (CN) | 2021-09-29 | — | — | EP | disclosed |
| CN-113166140-A | CDK8/19 inhibitors | 拜奥卡德联合股份公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-107207404-B | Compound, and separation method, synthesis method and application thereof | 北京北大维信生物科技有限公司 | 2021-07-13 | — | — | CN | disclosed |
| EP-3316885-B1 | ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | IMMUNOMEDICS INC (US) | 2021-06-23 | — | — | EP | disclosed |
| CN-110551081-B | Method for extracting 10-deacetylation baccatin III from taxus mairei | 无锡紫杉药业有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-112724183-A | Preparation method of arctiin | 蚌埠学院 | 2021-04-30 | — | — | CN | disclosed |
| CN-112645996-A | Peach blossom effective component capable of promoting blood coagulation and extraction and separation method and application thereof | 黄河科技学院 | 2021-04-13 | — | — | CN | disclosed |
| CN-112624928-A | Anticoagulant peach blossom effective component and application thereof | 黄河科技学院 | 2021-04-09 | — | — | CN | disclosed |
| CN-112624928-A | Anticoagulant peach blossom effective component and application thereof | 黄河科技学院 | 2021-04-09 | — | — | CN | disclosed |
| CN-107735090-B | antibody-SN-38 immunoconjugates with CL2A linkers | 免疫医疗公司 | 2021-04-06 | — | — | CN | disclosed |
| CN-112538016-A | Method for extracting chlorogenic acid n-butyl ester from peach blossom | 黄河科技学院 | 2021-03-23 | — | — | CN | disclosed |
| CN-112538016-A | Method for extracting chlorogenic acid n-butyl ester from peach blossom | 黄河科技学院 | 2021-03-23 | — | — | CN | disclosed |
| CN-109134580-B | Purified vinaginsenoside R extracted from ginseng leaves15Method (2) | 吉林大学 | 2020-10-30 | — | — | CN | disclosed |
| US-10751420-B2 | Antibody-SN-38 immunoconjugates with a CL2A linker | IMMUNOMEDICS, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| EP-3666770-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS CDK8/19 INHIBITORS | Joint Stock Company "Biocad" (RU) | 2020-06-17 | — | — | EP | disclosed |
| CN-111198244-A | Thin-layer chromatography detection method for nauclea officinalis extract syrup | 海南森祺制药有限公司 | 2020-05-26 | — | — | CN | disclosed |
| WO-2020027704-A1 | CDK8/19 INHIBITORS | ЗАКРЫТОЕ АКЦИОНЕРНОЕ ОБЩЕСТВО "БИОКАД" | 2020-02-06 | — | — | WO | disclosed |
| CN-110551081-A | method for extracting 10-deacetylation baccatin III from taxus mairei | JIANGSU YEW PHARMACEUTICAL CO LTD | 2019-12-10 | — | — | CN | disclosed |
| US-10406191-B2 | Compounds, extracts and methods from chinese medicinal herb sophora flavescens that inhibit airway contraction | Li, Xui-Min (US) | 2019-09-10 | — | — | US | disclosed |
| CN-107556358-B | Effective component of procoagulant cordyceps militaris and extraction and separation method and application thereof | 黄河科技学院 | 2019-08-23 | — | — | CN | disclosed |
| US-20190030175-A1 | ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | IMMUNOMEDICS, INC. | 2019-01-31 | — | — | US | disclosed |
| CN-109134580-A | One kind extraction purification vinaginsenoside R from folium panacis japonici cum caule15Method | 吉林大学 | 2019-01-04 | — | — | CN | disclosed |
| US-10143756-B2 | Antibody-SN-38 immunoconjugates with a CL2A linker | IMMUNOMEDICS, INC. (US) | 2018-12-04 | — | — | US | disclosed |
| US-10099998-B2 | Compound, and separation method, synthesis method and use thereof | BEIJING PEKING UNIVERSITY WBL BIOTECH CO., LTD. (CN) | 2018-10-16 | — | — | US | disclosed |
| US-10093695-B2 | Sterol derivative, preparation method therefor and use thereof | BEIJING PEKING UNIVERSITY WBL BIOTECH CO., LTD. (CN) | 2018-10-09 | — | — | US | disclosed |
| CN-108239098-A | Ben Bing Evil Qin oxazolidinone compounds containing tetrahydropyridine and its preparation method and application | 中国医学科学院药物研究所 | 2018-07-03 | — | — | CN | disclosed |
| US-20180161440-A1 | ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | JOHNSON MATTHEY PHARMACEUTICAL MATERIALS, INC. | 2018-06-14 | — | — | US | disclosed |
| EP-3316885-A1 | ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | Immunomedics, Inc. (US) | 2018-05-09 | — | — | EP | disclosed |
| US-9931417-B2 | Antibody-SN-38 immunoconjugates with a CL2A linker | IMMUNOMEDICS, INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-20180022688-A1 | COMPOUND, AND SEPARATION METHOD, SYNTHESIS METHOD AND USE THEREOF | BEIJING PEKING UNIVERSITY WBL BIOTECH CO., LTD. (CN) | 2018-01-25 | — | — | US | disclosed |
| CN-107556358-A | Effective component of procoagulant cordyceps militaris and extraction and separation method and application thereof | 黄河科技学院 | 2018-01-09 | — | — | CN | disclosed |
| CN-104159910-B | Sterol derivative and preparation method and application thereof | 北京北大维信生物科技有限公司 | 2017-02-15 | — | — | CN | disclosed |
| WO-2017004144-A1 | ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | IMMUNOMEDICS, INC. (US) | 2017-01-05 | — | — | WO | disclosed |
| US-20160303253-A1 | ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | JOHNSON MATTHEY PHARMACEUTICAL MATERIALS, INC. | 2016-10-20 | — | — | US | disclosed |
| US-20150359834-A1 | COMPOUNDS, EXTRACTS AND METHODS FROM CHINESE MEDICINAL HERB SOPHORA FLAVESCENS THAT INHIBIT AIRWAY CONTRACTION | LI, XIU-MIN | 2015-12-17 | — | — | US | disclosed |
| CN-103239459-B | Use of sterol derivative in preparation of medicines for preventing and/or treating and/or adjunctively treating cancers | UNIV BEIJING PEKING WBL BIOTECH CO LTD | 2015-03-11 | — | — | CN | disclosed |
| US-20150025130-A1 | STEROL DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING PEKING UNIVERSITY WBL BIOTECH CO., LTD. (CN) | 2015-01-22 | — | — | US | disclosed |
| CN-104159910-A | Sterol derivative and preparation method and application thereof | UNIV BEIJING PEKING WBL BIOTECH CO LTD | 2014-11-19 | — | — | CN | disclosed |
| US-8710247-B2 | Process to extract quassinoids | THE UNIVERSITY OF THE WEST INDIES (JM) | 2014-04-29 | — | — | US | disclosed |
| CN-103239459-A | Use of sterol derivative in preparation of medicines for preventing and/or treating and/or adjunctively treating cancers | UNIV BEIJING PEKING WBL BIOTECH CO LTD | 2013-08-14 | — | — | CN | disclosed |
| US-20130012726-A1 | PROCESS TO EXTRACT QUASSINOIDS | UNIVERSITY OF THE WEST INDIES, A REGIONAL INSTITUTION, ESTABLISHED BY ROYAL CHARTER | 2013-01-10 | — | — | US | disclosed |
| EP-1861359-B1 | N-(N-SULFONYLAMINOMETHYL)CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | PFIZER (US) | 2012-11-14 | — | — | EP | disclosed |
| US-8217187-B2 | Process to extract quassinoids | THE UNIVERSITY OF THE WEST INDIES (JM) | 2012-07-10 | — | — | US | disclosed |
| US-7915448-B2 | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as VR1 receptor antagonists | PFIZER INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-20100216821-A1 | Benzimidazoles With A Hetero Spiro-Decane Residue As NPY-Y5 Antagonists | BARTON NICHOLAS PAUL | 2010-08-26 | — | — | US | disclosed |
| US-7763621-B2 | Vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same | GALAPAGOS SAS (FR) | 2010-07-27 | — | — | US | disclosed |
| CN-101057895-B | 'Fuyanshu' preparation for treating gynopathy and its quality controlling method | BEIJING QIYUAN YIDE INST OF MATERIA MEDICA | 2010-05-19 | — | — | CN | disclosed |
| US-20100035880-A1 | SUBSTITUTED SULFONYLAMINOARYLMETHYL CYCLOPROPANECARBOXAMIDE AS VR1 RECEPTOR ANTAGONISTS | PFIZER INC | 2010-02-11 | — | — | US | disclosed |
| EP-2139861-A1 | BENZIMIDAZOLES WITH A HETERO SPIRO-DECANE RESIDUE AS NPY-Y5 ANTAGONISTS | Glaxo Group Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| US-7622589-B2 | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as VR1 receptor antagonists | PFIZER INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-7582640-B2 | Vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same | GALAPAGOS SAS (FR) | 2009-09-01 | — | — | US | disclosed |
| US-20090176809-A1 | RAF INHIBITOR COMPOUNDS AND METHODS | LAIRD ELLEN | 2009-07-09 | — | — | US | disclosed |
| US-20090171102-A1 | PROCESS TO EXTRACT QUASSINOIDS | THE UNIVERSITY OF THE WEST INDIES | 2009-07-02 | — | — | US | disclosed |
| US-7553972-B2 | Benzamide inhibitors of the P2X7 receptor | PFIZER, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-20090149476-A1 | Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same | GALAPAGOS SAS | 2009-06-11 | — | — | US | disclosed |
| US-7491829-B2 | RAF inhibitor compounds and methods | ARRAY BIOPHARMA INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-20090029996-A1 | phosphodiesterase enzyme inhibitor; 4-[(3-chlorophenyl)amino]-2-ethyl-5-(1-hydroxyethyl)-6-phenylpyridazin-3(2H)-one; potent antiinflammatory agent; asthma, atopic dermatitis, psoriasis, chronic obstructive pulmonary disease, rheumatoid arthritis, irritable bowel disease | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-01-29 | — | — | US | disclosed |
| WO-2008129007-A1 | BENZIMIDAZOLES WITH A HETERO SPIRO-DECANE RESIDUE AS NPY-Y5 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |
| US-7404972-B2 | Process to extract quassinoids | THE UNIVERSITY OF THE WEST INDIES (JM) | 2008-07-29 | — | — | US | disclosed |
| EP-1861359-A1 | N-(N-SULFONYLAMINOMETHYL)CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | Pfizer, Inc. (US) | 2007-12-05 | — | — | EP | disclosed |
| EP-1846391-A2 | RAF INHIBITOR COMPOUNDS AND METHODS | Genentech, Inc. (US) | 2007-10-24 | — | — | EP | disclosed |
| CN-101057895-A | 'Fuyanshu' preparation for treating gynopathy and its preparation method and quality controlling method and application | QIYUANYIDE MEDICINES INST BEIJ (CN) | 2007-10-24 | — | — | CN | disclosed |
| US-20070142329-A1 | Benzamide Inhibitors of the P2X7 Receptor | PFIZER INC. | 2007-06-21 | — | — | US | disclosed |
| EP-1781621-A1 | PYRIDAZIN-3(2H)-ONE DERIVATIVES AND THEIR USE AS PDE4 INHIBITORS | Laboratorios Almirall, S.A. (ES) | 2007-05-09 | — | — | EP | disclosed |
| US-7186742-B2 | Benzamide inhibitors of the P2X7 receptor | PFIZER INC (US) | 2007-03-06 | — | — | US | disclosed |
| US-20060281808-A1 | Process to extract quassinoids | THE UNIVERSITY OF THE WEST INDIES (JM) | 2006-12-14 | — | — | US | disclosed |
| WO-2006097817-A9 | N- (N-SULFONYLAMINOMETHYL) CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | PFIZER JAPAN INC (JP) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006097817-A1 | N- (N-SULFONYLAMINOMETHYL) CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | PFIZER JAPAN INC. (JP) | 2006-09-21 | — | — | WO | disclosed |
| US-20060211741-A1 | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as VR1 receptor antagonists | PFIZER, INC. | 2006-09-21 | — | — | US | disclosed |
| US-20060189627-A1 | RAF inhibitor compounds and methods | ARRAY BIOPHARMA INC. | 2006-08-24 | — | — | US | disclosed |
| WO-2006084015-A2 | RAF INHIBITOR COMPOUNDS AND METHODS | GENENTECH, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060052398-A1 | Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same | GALAPAGOS NV (BE) | 2006-03-09 | — | — | US | disclosed |
| WO-2005123693-A1 | PYRIDAZIN-3(2H)-ONE DERIVATIVES AND THEIR USE AS PDE4 INHIBITORS | LABORATORIOS ALMIRALL, S.A. (ES) | 2005-12-29 | — | — | WO | disclosed |
| US-20050009900-A1 | Benzamide inhibitors of the P2X7 receptor | ZOETIS LLC | 2005-01-13 | — | — | US | disclosed |
| EP-0979231-B1 | CONDENSED PYRIDAZINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-11-24 | — | — | EP | disclosed |
| EP-1123936-B1 | FUSED PYRIDAZINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-12-10 | — | — | EP | disclosed |
| US-6627630-B1 | Preventing or treating allergic skin diseases such as contact dermatitis, pruritus, dried dermatitis, acute urticaria prurigo and antiallergins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| EP-1123936-A1 | FUSED PYRIDAZINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-6248740-B1 | FOR SUPPRESSION OF HISTAMINE OR EOSINOPHIL CHEMOTAXIS TO TREAT ASTHMA; ANTIALLERGENIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0781283-B1 | TRIAZOLOPYRIDAZINES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-06-06 | — | — | EP | disclosed |
| EP-1059924-A1 | TRIAZOLO-PYRIDAZINE DERIVATIVES FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASES | Takeda Chemical Industries, Ltd. (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| CN-1248259-A | Fused pyridazine derivatives, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-03-22 | — | — | CN | disclosed |
| EP-0979231-A1 | CONDENSED PYRIDAZINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1999044611-A1 | TRIAZOLO-PYRIDAZINE DERIVATIVES FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-10 | — | — | WO | disclosed |
| EP-0562439-B1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0562440-B1 | Imidazopyridazines as antiasthmatics | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-12-23 | — | — | EP | disclosed |
| WO-1998049167-A1 | CONDENSED PYRIDAZINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |
| CN-1172478-A | Quinolone derivative antithrombotic agent | OTSUKA PHARMA CO LTD (JP) | 1998-02-04 | — | — | CN | disclosed |
| EP-0796248-A1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0781283-A1 | TRIAZOLOPYRIDAZINES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | Takeda Chemical Industries, Ltd. (JP) | 1997-07-02 | — | — | EP | disclosed |
| WO-1997012869-A1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-10 | — | — | WO | disclosed |
| WO-1996008496-A1 | TRIAZOLOPYRIDAZINES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-21 | — | — | WO | disclosed |
| US-5491145-A | ANTIASTHMA, ANTI-PLATELET ACTIVATING FACTOR BRONCHOCONSTRICTION-INHIBITING AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| US-5482939-A | ANTI-PLATELET ACTIVATING FACTOR ACTIVITIES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| US-5389633-A | ANTIASTHMATIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0444549-B1 | Imidazopyridazines their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-01-25 | — | — | EP | disclosed |
| EP-0562439-A1 | Triazolopyridazines as antioasthmatics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0562440-A1 | Imidazopyridazines as antiasthmatics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0287971-B1 | BENZIMIDAZOLE DERIVATIVES AND PROCESS FOR THEIR PREPARATIONS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |
| US-5145850-A | Antiasthmatic | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0444549-A1 | Imidazopyridazines their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-09-04 | — | — | EP | disclosed |
| US-4942245-A | ANTIALLERGIC AGENTS, ANTIASTHMATICS, RHINITIS, CONJUNCTIVITIS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-07-17 | — | — | US | disclosed |
| EP-0287971-A2 | Benzimidazole derivatives and process for their preparations | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |
| EP-0287971-A2 | Benzimidazole derivatives and process for their preparations | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (20 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052398-A1 | Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same | ADGRF1, C5AR2, ADGRE5 | TDP1 4779/4885TSHR 593/4885TRPV1 538/4885 |
| US-20180161440-A1 | ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | CLTA, CLTC, FCGR2A | TDP1 2917/4885TSHR 849/4885TRPV1 4872/4885 |
| US-20060211741-A1 | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as VR1 receptor antagonists | CNR1, HVCN1, CNR2 | TDP1 4384/4885TSHR 185/4885TRPV1 104/4885 |
| US-20090029996-A1 | phosphodiesterase enzyme inhibitor; 4-[(3-chlorophenyl)amino]-2-ethyl-5-(1-hydroxyethyl)-6-phenylpyridazin-3(2H)-one; potent antiinflammatory agent; asthma, atopic dermatitis, psoriasis, chronic obstructive pulmonary disease, rheumatoid arthritis, irritable bowel disease | PDE12, PDE4A, PDE4B | TDP1 296/4885TSHR 3235/4885TRPV1 1365/4885 |
| US-20160303253-A1 | ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | CLTA, CLTC, FCGR2A | TDP1 2917/4885TSHR 849/4885TRPV1 4872/4885 |
| US-20090149476-A1 | Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same | ADGRF1, C5AR2, ADGRE5 | TDP1 4779/4885TSHR 593/4885TRPV1 538/4885 |
| US-20230233694-A1 | ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | CLTA, CLTC, FCGR2A | TDP1 2917/4885TSHR 849/4885TRPV1 4872/4885 |
| US-20150025130-A1 | STEROL DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | HMGCR, CYP46A1, DHCR7 | TDP1 3944/4885TSHR 4029/4885TRPV1 4550/4885 |
| US-10751420-B2 | Antibody-SN-38 immunoconjugates with a CL2A linker | CLTA, CLTC, FCGR2A | TDP1 2917/4885TSHR 849/4885TRPV1 4872/4885 |
| US-20060189627-A1 | RAF inhibitor compounds and methods | BRAF, RAF1, ARAF | TDP1 983/4885TSHR 3255/4885TRPV1 4772/4885 |
| US-20180022688-A1 | COMPOUND, AND SEPARATION METHOD, SYNTHESIS METHOD AND USE THEREOF | HMGCR, COASY, DHCR7 | TDP1 3169/4885TSHR 4384/4885TRPV1 4711/4885 |
| US-20100035880-A1 | SUBSTITUTED SULFONYLAMINOARYLMETHYL CYCLOPROPANECARBOXAMIDE AS VR1 RECEPTOR ANTAGONISTS | CNR1, HVCN1, CNR2 | TDP1 4377/4885TSHR 165/4885TRPV1 106/4885 |
| US-20070142329-A1 | Benzamide Inhibitors of the P2X7 Receptor | IL1R1, P2RY1, P2RX1 | TDP1 1914/4885TSHR 412/4885TRPV1 29/4885 |
| US-20090176809-A1 | RAF INHIBITOR COMPOUNDS AND METHODS | BRAF, RAF1, ARAF | TDP1 983/4885TSHR 3255/4885TRPV1 4772/4885 |
| US-10093695-B2 | Sterol derivative, preparation method therefor and use thereof | HMGCR, CYP46A1, DHCR7 | TDP1 3944/4885TSHR 4029/4885TRPV1 4550/4885 |
| US-20050009900-A1 | Benzamide inhibitors of the P2X7 receptor | IL1R1, P2RY1, P2RX1 | TDP1 1914/4885TSHR 412/4885TRPV1 29/4885 |
| US-20190030175-A1 | ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | CLTA, CLTC, FCGR2A | TDP1 2917/4885TSHR 849/4885TRPV1 4872/4885 |
| US-10143756-B2 | Antibody-SN-38 immunoconjugates with a CL2A linker | CLTA, CLTC, FCGR2A | TDP1 2917/4885TSHR 849/4885TRPV1 4872/4885 |
| US-10099998-B2 | Compound, and separation method, synthesis method and use thereof | HMGCR, COASY, DHCR7 | TDP1 3169/4885TSHR 4384/4885TRPV1 4711/4885 |
| US-20100216821-A1 | Benzimidazoles With A Hetero Spiro-Decane Residue As NPY-Y5 Antagonists | NPY5R, NPY4R, NPY1R | TDP1 3912/4885TSHR 117/4885TRPV1 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.