Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.37 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14739660 | 0.80 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTNAMPT | |
| SCHEMBL7714854 | 0.78 | KMT2A (0.57) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL7708630 | 0.78 | KMT2A (0.56) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL2594688 | 0.74 | SLC6A4 (0.43) | ALDH1A1RHEB | |
| SCHEMBL14753482 | 0.74 | MAPT (0.43) | MEN1KMT2AALDH1A1MAPTNAMPT | |
| SCHEMBL14740366 | 0.73 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTNAMPT | |
| SCHEMBL14753479 | 0.73 | MAPT (0.41) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL14753480 | 0.73 | MAPT (0.45) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL14753481 | 0.72 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL2595477 | 0.71 | TUBB4A (0.54) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059850-A1 | AZA-INDOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2013-03-07 | — | — | US | claimed |
| US-20130059850-A1 | AZA-INDOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20130059850-A1 | AZA-INDOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059850-A1 | AZA-INDOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | FAAH, FAAH2, IDO1 | MEN1 3056/4885KMT2A 550/4885ALDH1A1 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.