Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1617397 | 0.71 | CYP2D6 (0.42) | GABRA1GABRB2SIGMAR1 | |
| SCHEMBL14692732 | 0.67 | ALDH1A1 (0.37) | GABRA1GABRB2 | |
| SCHEMBL2829867 | 0.66 | GABRA1 (0.37) | GABRA1GABRB2L3MBTL1ADRA2BADRA2C | |
| SCHEMBL2473490 | 0.65 | GABRA1 (0.39) | GABRA1GABRB2ADRA2BADRA2CADRB2 | |
| SCHEMBL2365122 | 0.65 | — | — | |
| SCHEMBL9280377 | 0.64 | CFTR (0.49) | L3MBTL1SIGMAR1 | |
| SCHEMBL29763626 | 0.63 | GABRA1 (0.56) | GABRA1GABRB2L3MBTL1ADRA2BADRA2C | |
| SCHEMBL173300 | 0.63 | GABRA1 (0.56) | GABRA1GABRB2L3MBTL1ADRA2BADRA2C | |
| SCHEMBL5519566 | 0.63 | HCAR2 (0.33) | GABRA1GABRB2SIGMAR1 | |
| SCHEMBL7789544 | 0.63 | CYP2D6 (0.44) | GABRA1GABRB2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059924-A1 | PHOTOSTABILISERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059924-A1 | PHOTOSTABILISERS | ALDH1A1, ALDH18A1, ALDH1A2 | GABRA1 2453/4885GABRB2 2630/4885L3MBTL1 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.