SCHEMBL14743135

SCHEMBL14743135

C[Si]1(C)CCCC[Si](C)(C)[Si]1(c1ccccc1)c1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17885704 0.77 APOBEC3A (0.31)
SCHEMBL17885703 0.75 CYP2B6 (0.30)
SCHEMBL22164425 0.74
Ammonia Solution, Strong SCHEMBL27725623 0.73
SCHEMBL6440299 0.72 APOBEC3A (0.31)
SCHEMBL1426708 0.71 CALM1 (0.41)
SCHEMBL1249832 0.71 CALM1 (0.41)
SCHEMBL1425981 0.71 CALM1 (0.41)
SCHEMBL3886820 0.70 LMNA (0.33)
SCHEMBL3798583 0.70 MAPT (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9287114-B2 Method of modifying surfaces UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2016-03-15 US claimed
US-20140203414-A1 Method Of Modifying Surfaces UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2014-07-24 US claimed
EP-2748352-A1 METHOD OF MODIFYING SURFACES University Court of The University of St Andrews (GB) 2014-07-02 EP claimed
WO-2013030516-A1 METHOD OF MODIFYING SURFACES UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2013-03-07 WO claimed
US-9287114-B2 Method of modifying surfaces UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2016-03-15 US disclosed
US-20140203414-A1 Method Of Modifying Surfaces UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2014-07-24 US disclosed
EP-2748352-A1 METHOD OF MODIFYING SURFACES University Court of The University of St Andrews (GB) 2014-07-02 EP disclosed
WO-2013030516-A1 METHOD OF MODIFYING SURFACES UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2013-03-07 WO disclosed