Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743611 | 0.89 | MAPT (0.55) | OPRK1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL14744312 | 0.88 | NOTUM (0.51) | MEN1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL14744301 | 0.84 | AGTR1 (0.49) | MEN1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL14743051 | 0.84 | ALDH1A1 (0.48) | MEN1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL14743695 | 0.83 | RAB9A (0.54) | MEN1RAB9AKMT2AMAPTLMNA | |
| SCHEMBL14743792 | 0.79 | KMT2A (0.48) | MEN1RAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL14743310 | 0.78 | MEN1 (0.52) | MEN1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL14743400 | 0.78 | KMT2A (0.51) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL2635701 | 0.78 | MEN1 (0.60) | MEN1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL14743705 | 0.77 | MEN1 (0.51) | MEN1RAB9AKMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | claimed |
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |