Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743980 | 0.88 | NPC1 (0.51) | AGTR1RAB9AKDM4EAKR1C3MAPT | |
| SCHEMBL14743409 | 0.84 | OPRK1 (0.46) | RAB9AMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL14743051 | 0.82 | ALDH1A1 (0.48) | RAB9AKDM4EMAPTALDH1A1GAA | |
| SCHEMBL14743705 | 0.80 | MEN1 (0.51) | RAB9AKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL14743792 | 0.77 | KMT2A (0.48) | RAB9AKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL19707579 | 0.76 | MRGPRX4 (0.58) | AGTR1RAB9AKDM4EAKR1C3MAPT | |
| SCHEMBL14743400 | 0.76 | KMT2A (0.51) | KDM4EMAPTALDH1A1GAAKMT2A | |
| SCHEMBL14743310 | 0.76 | MEN1 (0.52) | RAB9AKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL14744312 | 0.76 | NOTUM (0.51) | RAB9AMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL14743695 | 0.75 | RAB9A (0.54) | RAB9AKDM4EMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | claimed |
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |