Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743672 | 0.90 | KCNMA1 (0.50) | MEN1KMT2AHDAC1KCNMA1KDM4E | |
| SCHEMBL14742913 | 0.87 | RAB9A (0.49) | MEN1KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL14743685 | 0.86 | KCNMA1 (0.55) | MEN1KMT2AHDAC1KCNMA1KDM4E | |
| SCHEMBL14744028 | 0.86 | GRM4 (0.53) | HDAC1HDAC8HDAC6MAPT | |
| SCHEMBL14743695 | 0.84 | RAB9A (0.54) | MEN1KMT2AKDM4ENPSR1MAPT | |
| SCHEMBL14743310 | 0.82 | MEN1 (0.52) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL14744301 | 0.80 | AGTR1 (0.49) | MEN1KMT2AKDM4ENPSR1MAPT | |
| SCHEMBL14743367 | 0.80 | GAA (0.55) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL14743580 | 0.80 | CFD (0.50) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL14743374 | 0.80 | SORT1 (0.44) | MEN1KMT2AKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | claimed |
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |