Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.44 |
| ▸ | KDM6B | O15054 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086655 | 0.85 | KDM4C (0.45) | KDM4EKDM4CKDM6BALDH1A1GLA | |
| SCHEMBL798742 | 0.84 | KDM4C (0.42) | KDM4CKDM6BALDH1A1GAAKMT2A | |
| SCHEMBL16094860 | 0.81 | TDP1 (0.55) | KDM4EADORA3KDM4CKDM6BALDH1A1 | |
| SCHEMBL17465921 | 0.79 | KDM4C (0.53) | KDM4EKDM4CKDM6BALDH1A1GLA | |
| SCHEMBL14084348 | 0.79 | KDM4C (0.41) | KDM4ECYP3A4CYP2C19KDM4CKDM6B | |
| SCHEMBL13518160 | 0.78 | KDM4E (0.55) | KDM4ECYP1A2CYP3A4MPOADORA3 | |
| SCHEMBL2989594 | 0.77 | KDM4E (0.50) | KDM4ECYP1A2CYP3A4MPOADORA3 | |
| SCHEMBL799283 | 0.77 | KDM4C (0.37) | KDM4CKDM6BALDH1A1MAPTNPC1 | |
| SCHEMBL24480200 | 0.77 | CTSD (0.55) | ALDH1A1P2RX7GAATDP1MEN1 | |
| SCHEMBL15110200 | 0.74 | AOC1 (0.50) | KDM4ECYP1A2CYP3A4MPOADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030794-A2 | USE OF SUBSTITUTED PYRIDINES AS SKIN DEPIGMENTING COMPOUNDS | KASRAEE BEHROOZ (CH) | 2013-03-07 | — | — | WO | claimed |
| US-9694014-B2 | Treatment of muscular dystrophies and associated conditions by administration of monoamine oxidase inhibitors | UNIVERSITA DEGLI STUDI DI PADOVA (IT) | 2017-07-04 | — | — | US | disclosed |
| US-20150290201-A1 | TREATMENT OF MUSCULAR DYSTROPHIES AND ASSOCIATED CONDITIONS BY ADMINISTRATION OF MONOAMINE OXIDASE INHIBITORS | UNIV PADOVA (IT) | 2015-10-15 | — | — | US | disclosed |
| US-8487008-B2 | Treatment of muscular dystrophies and associated conditions by administration of monoamine oxidase inhibitors | UNIVERSITA DEGLI STUDI DI PADOVA (IT) | 2013-07-16 | — | — | US | disclosed |
| WO-2013030794-A2 | USE OF SUBSTITUTED PYRIDINES AS SKIN DEPIGMENTING COMPOUNDS | KASRAEE BEHROOZ (CH) | 2013-03-07 | — | — | WO | disclosed |
| CN-102822165-A | Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same | CELGENE CORP | 2012-12-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150290201-A1 | TREATMENT OF MUSCULAR DYSTROPHIES AND ASSOCIATED CONDITIONS BY ADMINISTRATION OF MONOAMINE OXIDASE INHIBITORS | MAOA, MAOB, MUSK | KDM4E 1801/4885CYP1A2 328/4885CYP3A4 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.