Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743807 | 0.91 | HPGDS (0.40) | HPGDSTDP1CHRM4NTRK1GAA | |
| SCHEMBL14743626 | 0.88 | GAA (0.48) | GAAALDH1A1TSHRHPGDALOX15 | |
| SCHEMBL14743819 | 0.85 | LMNA (0.34) | TDP1CHRM4GAAALDH1A1TSHR | |
| SCHEMBL14743424 | 0.85 | TDP1 (0.52) | TDP1ALDH1A1CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL14743068 | 0.84 | PSMD14 (0.38) | CHRM4NTRK1ALDH1A1 | |
| SCHEMBL14743576 | 0.84 | KMT2A (0.48) | TDP1GAAALDH1A1CYP2C9HPGD | |
| SCHEMBL14743033 | 0.84 | TDP1 (0.41) | HPGDSTDP1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL14742993 | 0.83 | GAA (0.34) | TDP1NTRK1VNN1GAAALDH1A1 | |
| SCHEMBL14743644 | 0.82 | TDP1 (0.40) | TDP1CHRM4ALDH1A1OPRM1OPRL1 | |
| SCHEMBL14743411 | 0.76 | TDP1 (0.50) | TDP1GAAALDH1A1CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | claimed |
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |