Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743642 | 0.91 | HPGDS (0.37) | HPGDSTDP1CHRM4NTRK1HTT | |
| SCHEMBL14743709 | 0.86 | ALOX15 (0.37) | TDP1HTTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14743411 | 0.86 | TDP1 (0.50) | TDP1HTTALDH1A1HPGDTSHR | |
| SCHEMBL14743956 | 0.85 | PSMD14 (0.36) | TDP1CHRM4NTRK1RAB9AALDH1A1 | |
| SCHEMBL14743000 | 0.84 | ALDH1A1 (0.35) | TDP1HTTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14743911 | 0.83 | ALDH1A1 (0.39) | TDP1CHRM4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL14743626 | 0.79 | GAA (0.48) | RAB9AHTTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14743664 | 0.77 | ALDH1A1 (0.36) | RAB9AHTTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14743641 | 0.77 | RAB9A (0.45) | MRGPRX4RAB9AHPGDGPBAR1SMN1; SMN2 | |
| SCHEMBL14743424 | 0.76 | TDP1 (0.52) | TDP1HTTALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |