Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743819 | 0.90 | LMNA (0.34) | ALOX15ALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL14743956 | 0.87 | PSMD14 (0.36) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL14743807 | 0.86 | HPGDS (0.40) | ALOX15HTTALDH1A1LMNAHPGD | |
| SCHEMBL14743911 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL14743000 | 0.84 | ALDH1A1 (0.35) | ALOX15HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL14743411 | 0.84 | TDP1 (0.50) | HTTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL14743664 | 0.81 | ALDH1A1 (0.36) | HTTALDH1A1KMT2AMEN1NQO2 | |
| SCHEMBL14743626 | 0.79 | GAA (0.48) | ALOX15HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL14743068 | 0.77 | PSMD14 (0.38) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL14743576 | 0.77 | KMT2A (0.48) | HTTALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |