Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743830 | 0.81 | MAPT (0.43) | GPR35HPGDALOX15USP2POLB | |
| SCHEMBL2896018 | 0.77 | GPR35 (0.63) | GPR35HPGDALOX15USP2POLB | |
| Hydrochloric Acid SCHEMBL11746382 | 0.76 | GPR35 (0.61) | GPR35HPGDALOX15USP2POLB | |
| SCHEMBL26581240 | 0.68 | PIM1 (0.45) | GPR35HPGDALOX15USP2POLB | |
| SCHEMBL19665842 | 0.68 | MCL1 (0.57) | GPR35HPGDALOX15USP2POLB | |
| SCHEMBL29526778 | 0.67 | PIM1 (0.64) | GPR35HSD17B10KDM4EALDH1A1CYP1A2 | |
| SCHEMBL175987 | 0.67 | ALDH1A1 (0.59) | HPGDUSP2POLBHSD17B10KDM4E | |
| SCHEMBL705754 | 0.67 | PIM1 (0.64) | GPR35HSD17B10KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9068668 | 0.67 | GPR35 (1.00) | GPR35HPGDALOX15USP2POLB | |
| SCHEMBL5563631 | 0.67 | ALDH1A1 (0.58) | GPR35HPGDALOX15USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |