Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 14/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31226055 | 0.80 | KMT2A (0.55) | SMN1; SMN2SENP1 | |
| SCHEMBL257153 | 0.79 | MMP9 (0.57) | PSIP1RORCSMN1; SMN2MMP9 | |
| SCHEMBL9059841 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2SENP1 | |
| SCHEMBL31226071 | 0.79 | SENP1 (0.61) | SMN1; SMN2SENP1 | |
| SCHEMBL2665972 | 0.78 | KMT2A (0.57) | PSIP1RORCSMN1; SMN2 | |
| SCHEMBL31225821 | 0.78 | KMT2A (0.52) | SMN1; SMN2SENP1 | |
| SCHEMBL6937307 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2SENP1 | |
| SCHEMBL5716133 | 0.77 | HPGD (0.54) | SMN1; SMN2 | |
| SCHEMBL31225539 | 0.76 | KMT2A (0.51) | SMN1; SMN2SENP1 | |
| SCHEMBL5715921 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |