SCHEMBL14744262

SCHEMBL14744262

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nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.36
ALPL P05186 1/20 0.35
POLB P06746 1/20 0.35
ALPG P10696 1/20 0.35
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
BBOX1 O75936 1/20 0.32
GABRP O00591 2/20 0.31
GABRD O14764 2/20 0.31
GABRA1 P14867 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22479145 1.00 GABRR1 (0.36) GABRR1ALPLPOLBALPGCHRM1
SCHEMBL22479229 0.80 GABRR1 (0.52) GABRR1ALPLPOLBALPGCHRM1
SCHEMBL5538444 0.80 CHRM1 (0.50) GABRR1ALPLPOLBALPGCHRM1
SCHEMBL7505468 0.79 OR51E2 (0.39) GABRR1ALPLPOLBALPGOR51E2
SCHEMBL172177 0.79 OR51E2 (0.39) GABRR1ALPLPOLBALPGOR51E2
SCHEMBL13276094 0.78 CYP1A2 (0.50) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL631293 0.78 POLB (0.47) ALPLPOLBALPGBBOX1TSHR
SCHEMBL5531470 0.76 CA2 (0.50) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL29998997 0.75 RNPEP (0.52) GABRR1ALPLPOLBALPG
SCHEMBL5533707 0.75 GPR84 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150164069-A1 INSECTICIDAL LIPID AGENTS ISOLATED FROM ENTOMOPATHOGENIC FUNGI AND USES THEREOF BIOTELLIGA HOLDINGS LIMITED (NZ) 2015-06-18 US disclosed
EP-2751070-A1 INSECTICIDAL LIPID AGENTS ISOLATED FROM ENTOMOPATHOGENIC FUNGI AND USES THEREOF Biotelliga Holdings Limited (NZ) 2014-07-09 EP disclosed
WO-2013030792-A1 INSECTICIDAL LIPID AGENTS ISOLATED FROM ENTOMOPATHOGENIC FUNGI AND USES THEREOF BIOTELLIGA HOLDINGS LIMITED (NZ) 2013-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150164069-A1 INSECTICIDAL LIPID AGENTS ISOLATED FROM ENTOMOPATHOGENIC FUNGI AND USES THEREOF ERG28, LIPC, SGMS2 GABRR1 1506/4885ALPL 492/4885POLB 4644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.