Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743613 | 0.90 | SENP1 (0.44) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL14744302 | 0.83 | ACLY (0.46) | ALDH1A1HPGDRAB9AMAPTMEN1 | |
| SCHEMBL14743833 | 0.79 | MAPT (0.38) | ALDH1A1HPGDRAB9AMAPTKMT2A | |
| SCHEMBL14743489 | 0.77 | GAA (0.41) | GAARAB9AKMT2ANPC1HSD17B10 | |
| SCHEMBL14743723 | 0.76 | KDM4E (0.47) | KDM4EKMT2A | |
| SCHEMBL14743695 | 0.75 | RAB9A (0.54) | KDM4EGAARAB9AMAPTMEN1 | |
| SCHEMBL14743459 | 0.75 | ACLY (0.36) | ALDH1A1HPGDRAB9AMAPTNPC1 | |
| SCHEMBL14743702 | 0.75 | TPMT (0.40) | HPGDRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL14743979 | 0.74 | TSHR (0.42) | ALDH1A1HPGDRAB9AMAPTMEN1 | |
| SCHEMBL14743805 | 0.74 | GPBAR1 (0.43) | ALDH1A1KDM4EGAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | claimed |
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |