Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515825 | 0.81 | DPP4 (0.57) | CSNK2A2CSNK2BCSNK2A1CSNK2A3DPP4 | |
| SCHEMBL479743 | 0.78 | CYP3A4 (0.46) | CYP3A4NFKB1PMP22ALDH1A1SMN1; SMN2 | |
| SCHEMBL14744534 | 0.77 | MAPT (0.48) | CYP3A4ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3467784 | 0.76 | CYP3A4 (0.48) | CYP3A4NFKB1PMP22ALDH1A1SMN1; SMN2 | |
| SCHEMBL7969110 | 0.75 | PLA2G7 (0.66) | DPP4CYP3A4NFKB1PMP22PLA2G7 | |
| SCHEMBL27150508 | 0.74 | DPP4 (0.44) | CSNK2A2CSNK2BCSNK2A1CSNK2A3DPP4 | |
| SCHEMBL30839727 | 0.73 | CYP3A4 (0.65) | CYP3A4NFKB1PMP22PLA2G7ALDH1A1 | |
| SCHEMBL302092 | 0.73 | CYP3A4 (0.65) | CYP3A4NFKB1PMP22PLA2G7ALDH1A1 | |
| SCHEMBL5579085 | 0.72 | GRM2 (0.40) | CSNK2A2CSNK2BCSNK2A1CSNK2A3TP53 | |
| SCHEMBL6898343 | 0.71 | ALDH1A1 (0.44) | CSNK2A2CSNK2BCSNK2A1CSNK2A3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |