Sugi Predict

Sugi Predict / Compounds / SCHEMBL1474670

SCHEMBL1474670

SCHEMBL1474670

C=C(C)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 2/20 0.54
▸ CES1 P23141 2/20 0.54
▸ NR4A1 P22736 1/20 0.50
▸ NR4A2 P43354 1/20 0.50
▸ NR4A3 Q92570 1/20 0.50
▸ PTGS1 P23219 4/20 0.47
▸ PTGS2 P35354 2/20 0.47
▸ NQO2 P16083 1/20 0.47
▸ SRD5A2 P31213 1/20 0.47
▸ GSK3B P49841 2/20 0.45
▸ PTPN1 P18031 1/20 0.45
▸ CYP1A1 P04798 1/20 0.43
▸ CYP1B1 Q16678 1/20 0.43
▸ ORAI1 Q96D31 1/20 0.43
▸ ORAI2 Q96SN7 1/20 0.43
▸ ORAI3 Q9BRQ5 1/20 0.43
▸ TRPV6 Q9H1D0 1/20 0.43
▸ KIF11 P52732 1/20 0.43
▸ MGLL Q99685 1/20 0.43
▸ TRPV1 Q8NER1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11352831 0.88 MAOB (0.46) CES2CES1NR4A1NR4A2NR4A3
SCHEMBL20616201 0.82 CES2 (0.35) CES2CES1NR4A1NR4A2NR4A3
SCHEMBL26474236 0.80 TSHR (0.35) CES2CES1NR4A1NR4A2NR4A3
SCHEMBL86047 0.80 NR1H3 (0.53) —
SCHEMBL1476091 0.80 PDE2A (0.46) CES2CES1NR4A1NR4A2NR4A3
SCHEMBL28243558 0.80 CES2 (0.58) CES2CES1NR4A1NR4A2NR4A3
SCHEMBL18242237 0.80 CES2 (0.58) CES2CES1NR4A1NR4A2NR4A3
SCHEMBL7253138 0.79 PDE2A (0.43) CES2CES1NR4A1NR4A2NR4A3
SCHEMBL56361 0.79 MAPT (0.40) CES2CES1
SCHEMBL11627251 0.79 TSHR (0.39) CES2CES1NR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116875181-B High-hardness hydrophobic finish varnish and preparation method thereof 广东美涂士建材股份有限公司 2024-07-23 — — CN claimed
CN-116875181-A High-hardness hydrophobic finish varnish and preparation method thereof 广东美涂士建材股份有限公司 2023-10-13 — — CN claimed
CN-119638660-A Preparation method of 3, 4-dihydropyran derivative 华侨大学 2025-03-18 — — CN disclosed
CN-116875181-B High-hardness hydrophobic finish varnish and preparation method thereof 广东美涂士建材股份有限公司 2024-07-23 — — CN disclosed
WO-2024128040-A1 ACTIVE-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMATION METHOD, AND ELECTRONIC DEVICE PRODUCTION METHOD 富士フイルム株式会社 2024-06-20 — — WO disclosed
WO-2023227696-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 — — WO disclosed
US-20230357258-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS ENANTA PHARMACEUTICALS, INC. 2023-11-09 — — US disclosed
CN-116875181-A High-hardness hydrophobic finish varnish and preparation method thereof 广东美涂士建材股份有限公司 2023-10-13 — — CN disclosed
WO-2023196454-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS ENANTA PHARMACEUTICALS, INC. (US) 2023-10-12 — — WO disclosed
US-20230324797-A1 POSITIVE RESIST COMPOSITION FOR EXTREME ULTRAVIOLET LITHOGRAPHY AND RESIST PATTERN FORMATION KIT FOR EXTREME ULTRAVIOLET LITHOGRAPHY ZEON CORPORATION (JP) 2023-10-12 — — US disclosed
US-20230324797-A1 POSITIVE RESIST COMPOSITION FOR EXTREME ULTRAVIOLET LITHOGRAPHY AND RESIST PATTERN FORMATION KIT FOR EXTREME ULTRAVIOLET LITHOGRAPHY ZEON CORPORATION (JP) 2023-10-12 — — US disclosed
EP-1353217-A1 Optical alignment method and liquid crystal display element JSR Corporation (JP) 2003-10-15 — — EP disclosed
US-20030087045-A1 Liquid crystal aligning agent and liquid crystal display element JSR CORPORATION (JP) 2003-05-08 — — US disclosed
EP-1305297-A1 BENZOTRIAZOLES CONTAINING ALPHA-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH Ciba SC Holding AG (CH) 2003-05-02 — — EP disclosed
US-20030004235-A1 Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORP. 2003-01-02 — — US disclosed
US-6451887-B1 Benzotriazoles containing α-cumyl groups substituted by heteroatoms and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION 2002-09-17 — — US disclosed
WO-2002012205-A1 BENZOTRIAZOLES CONTAINING α-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-02-14 — — WO disclosed
US-6124070-A STABILITY UNDER HIGH HUMIDITY AND AT LOW TEMPERATURE-LOW HUMIDITY, FINE PARTICLE SIZE AND A SHARP PARTICLE DIAMETER DISTRIBUTION; COMPRISING A BINDER RESIN, A COLORANT, A METHANOL-SOLUBLE RESIN HAVING ORGANIC ACID GROUPS CANON KABUSHIKI KAISHA (JP) 2000-09-26 — — US disclosed
EP-0182166-B1 PROCESS FOR PREPARING PHENYLISOPROPYLUREA COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1989-05-31 — — EP disclosed
US-4578513-A Process for preparing phenylisopropylurea compounds AMERICAN CYANAMID COMPANY (US) 1986-03-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357258-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS ACE, HPRT1, ACE2 CES2 3080/4885CES1 787/4885NR4A1 2814/4885
US-20030004235-A1 Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith SUV39H1, SUV39H2, TPST2 CES2 1684/4885CES1 3530/4885NR4A1 1179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.