Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746790 | 0.78 | ALDH1A1 (0.38) | LMNAGAA | |
| SCHEMBL29074273 | 0.72 | RAB9A (0.54) | AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL28456552 | 0.72 | RORC (0.43) | LMNA | |
| SCHEMBL8531927 | 0.72 | CYP19A1 (0.43) | TDP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL28529302 | 0.67 | EPAS1 (0.37) | AKR1C3AKR1C2TDP1LMNAMAPT | |
| SCHEMBL9367150 | 0.66 | AKR1C3 (0.50) | AKR1C3AKR1C2TDP1LMNAMAPT | |
| SCHEMBL14746841 | 0.66 | PTGS2 (0.50) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL1360458 | 0.64 | PSD (0.39) | AKR1C3AKR1C2PSDMAPTMEN1 | |
| SCHEMBL16923592 | 0.64 | HTT (0.62) | AKR1C3AKR1C2TDP1MAPTHTT | |
| SCHEMBL1744862 | 0.64 | ALDH1A1 (0.53) | TDP1LMNAMAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |