Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.37 |
| ▸ | VEGFA | P15692 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28536731 | 0.80 | ACLY (0.35) | ADORA2AADORA1ACLYSMN1; SMN2POLB | |
| SCHEMBL14744335 | 0.70 | GRIA1 (0.39) | ACLYGRIA1CACNG8 | |
| SCHEMBL7082751 | 0.69 | ALDH1A1 (0.39) | EPAS1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL7615427 | 0.68 | AKR1C2 (0.45) | MEN1KMT2ATDP1TTRMAPT | |
| SCHEMBL23580466 | 0.67 | GRIN2D (0.42) | HCRTR1PKMMEN1KMT2ATDP1 | |
| SCHEMBL14747018 | 0.67 | AKR1C3 (0.39) | MEN1KMT2ATDP1MAPTAKR1C3 | |
| SCHEMBL28429949 | 0.66 | TSHR (0.47) | HCRTR1PKMTDP1ABCC8KCNJ11 | |
| SCHEMBL8863198 | 0.66 | ALDH1A1 (0.44) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL7081702 | 0.66 | TLR8 (0.44) | EPAS1MEN1KMT2ATDP1MAPT | |
| SCHEMBL8083183 | 0.66 | TSHR (0.44) | EPAS1VEGFAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635970-B | Benzimidazolone and benzothiazolone compounds and their use as AMPA receptor modulators | 詹森药业有限公司 | 2021-03-12 | — | — | CN | disclosed |